Lutetium-177 therapeutic radiopharmaceuticals: linking chemistry, radiochemistry, and practical applications

S Banerjee, MRA Pillai, FF Knapp - Chemical reviews, 2015 - ACS Publications
Interest in the use of radionuclides for treatment of various diseases has a long history and
parallels the isolation of radium by Marie and Pierre Curie in the early part of the 20th …

Transarterial Radioembolization (TARE) Agents beyond 90Y‐Microspheres

C Bouvry, X Palard, J Edeline… - BioMed Research …, 2018 - Wiley Online Library
Liver malignancies, either primary tumours (mainly hepatocellular carcinoma and
cholangiocarcinoma) or secondary hepatic metastases, are a major cause of death, with an …

Nanoparticulate carrier containing water-insoluble iodinated oil as a multifunctional contrast agent for computed tomography imaging

WH Kong, WJ Lee, ZY Cui, KH Bae, TG Park, JH Kim… - Biomaterials, 2007 - Elsevier
Contrast-enhanced computed tomography (CT) imaging is a valuable and routine strategy
for the clinical diagnosis of various diseases. However, all current CT contrast agents are …

Radionuclide generators

F Rösch, FF Knapp - Handbook of nuclear chemistry, 2011 - ui.adsabs.harvard.edu
Radionuclide generator systems continue to play a key role in providing both diagnostic and
therapeutic radionuclides for various applications in nuclear medicine, oncology, and …

Iodinated oil-loaded, fluorescent mesoporous silica-coated iron oxide nanoparticles for magnetic resonance imaging/computed tomography/fluorescence trimodal …

S Xue, Y Wang, M Wang, L Zhang, X Du… - International Journal …, 2014 - Taylor & Francis
In this study, a novel magnetic resonance imaging (MRI)/computed tomography
(CT)/fluorescence trifunctional probe was prepared by loading iodinated oil into fluorescent …

Therapy with 188Re-Labeled Radiopharmaceuticals: An Overview of Promising Results from Initial Clinical Trials

JM Jeong, JK Chung - Cancer Biotherapy and …, 2003 - liebertpub.com
The development of an in-house 188W/188Re-generator has greatly increased the use of
188Re for treating various diseases. 188Re is of widespread interest due to its attractive …

Intra-arterial rhenium-188 lipiodol in the treatment of inoperable hepatocellular carcinoma: results of an IAEA-sponsored multination study

P Bernal, JL Raoul, G Vidmar, E Sereegotov… - International Journal of …, 2007 - Elsevier
PURPOSE: Intra-arterial injections (IAI) of 131I-lipiodol is effective in treating hepatocellular
carcinoma patients, but is expensive and requires a 7-day hospitalization in a …

Clinical applications of 188Re-labelled radiopharmaceuticals for radionuclide therapy

B Lambert, JMH de Klerk - Nuclear Medicine Communications, 2006 - journals.lww.com
Abstract 188 Re is a radionuclide in which there is widespread interest for therapeutic
purposes because of its favourable physical characteristics. Moreover, it can be eluted from …

188Re-HDD/lipiodol therapy for hepatocellular carcinoma: a phase I clinical trial

B Lambert, K Bacher, L Defreyne… - Journal of Nuclear …, 2005 - Soc Nuclear Med
The aim of this study was to investigate the pharmacokinetics, organ dosimetry, and toxicity
after the intraarterial administration of 188Re-labeled 4-hexadecyl-1, 2, 9, 9-tetramethyl-4, 7 …

188W/188Re Generator System and Its Therapeutic Applications

A Boschi, L Uccelli, M Pasquali, A Duatti… - Journal of …, 2014 - Wiley Online Library
The 188Re radioisotope represents a useful radioisotope for the preparation of
radiopharmaceuticals for therapeutic applications, particularly because of its favorable …