Super-resolution ultrasound imaging

K Christensen-Jeffries, O Couture, PA Dayton… - Ultrasound in medicine …, 2020 - Elsevier
The majority of exchanges of oxygen and nutrients are performed around vessels smaller
than 100 μm, allowing cells to thrive everywhere in the body. Pathologies such as cancer …

Ultrasound contrast imaging: Fundamentals and emerging technology

H Yusefi, B Helfield - Frontiers in Physics, 2022 - frontiersin.org
The development of microbubble contrast agents has broadened the scope of medical
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …

Functional ultrasound localization microscopy reveals brain-wide neurovascular activity on a microscopic scale

N Renaudin, C Demené, A Dizeux, N Ialy-Radio… - Nature …, 2022 - nature.com
The advent of neuroimaging has increased our understanding of brain function. While most
brain-wide functional imaging modalities exploit neurovascular coupling to map brain …

Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients

C Demené, J Robin, A Dizeux, B Heiles… - Nature biomedical …, 2021 - nature.com
Abstract Changes in cerebral blood flow are associated with stroke, aneurysms, vascular
cognitive impairment, neurodegenerative diseases and other pathologies. Brain …

Performance benchmarking of microbubble-localization algorithms for ultrasound localization microscopy

B Heiles, A Chavignon, V Hingot, P Lopez… - Nature Biomedical …, 2022 - nature.com
Ultrafast ultrasound localization microscopy can be used to detect the subwavelength
acoustic scattering of intravenously injected microbubbles to obtain haemodynamic maps of …

Mapping the fine-scale organization and plasticity of the brain vasculature

C Kirst, S Skriabine, A Vieites-Prado, T Topilko… - Cell, 2020 - cell.com
The cerebral vasculature is a dense network of arteries, capillaries, and veins. Quantifying
variations of the vascular organization across individuals, brain regions, or disease models …

Deep learning in ultrasound imaging

RJG Van Sloun, R Cohen, YC Eldar - Proceedings of the IEEE, 2019 - ieeexplore.ieee.org
In this article, we consider deep learning strategies in ultrasound systems, from the front end
to advanced applications. Our goal is to provide the reader with a broad understanding of …

3D transcranial ultrasound localization microscopy in the rat brain with a multiplexed matrix probe

A Chavignon, B Heiles, V Hingot… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Objective: Ultrasound Localization Microscopy (ULM) provides images of the
microcirculation in-depth in living tissue. However, its implementation in two-dimension is …

Short acquisition time super-resolution ultrasound microvessel imaging via microbubble separation

C Huang, MR Lowerison, JD Trzasko, A Manduca… - Scientific reports, 2020 - nature.com
Super-resolution ultrasound localization microscopy (ULM), based on localization and
tracking of individual microbubbles (MBs), offers unprecedented microvascular imaging …

Aging-related cerebral microvascular changes visualized using ultrasound localization microscopy in the living mouse

MR Lowerison, NVC Sekaran, W Zhang, Z Dong… - Scientific reports, 2022 - nature.com
Aging-related cognitive decline is an emerging health crisis; however, no established
unifying mechanism has been identified for the cognitive impairments seen in an aging …