Molecular interactions between plants and insect herbivores

M Erb, P Reymond - Annual review of plant biology, 2019 - annualreviews.org
Diverse molecular processes regulate the interactions between plants and insect
herbivores. Here, we review genes and proteins that are involved in plant–herbivore …

Nitrate transport, signaling, and use efficiency

YY Wang, YH Cheng, KE Chen… - Annual review of plant …, 2018 - annualreviews.org
Nitrogen accounts for approximately 60% of the fertilizer consumed each year; thus, it
represents one of the major input costs for most nonlegume crops. Nitrate is one of the two …

Single-cell multi-omics in the medicinal plant Catharanthus roseus

C Li, JC Wood, AH Vu, JP Hamilton… - Nature Chemical …, 2023 - nature.com
Advances in omics technologies now permit the generation of highly contiguous genome
assemblies, detection of transcripts and metabolites at the level of single cells and high …

Single-cell RNA sequencing provides a high-resolution roadmap for understanding the multicellular compartmentation of specialized metabolism

S Sun, X Shen, Y Li, Y Li, S Wang, R Li, H Zhang… - Nature plants, 2023 - nature.com
Monoterpenoid indole alkaloids (MIAs) are among the most diverse specialized metabolites
in plants and are of great pharmaceutical importance. We leveraged single-cell …

The scaffold-forming steps of plant alkaloid biosynthesis

BR Lichman - Natural Product Reports, 2021 - pubs.rsc.org
Alkaloids from plants are characterised by structural diversity and bioactivity, and maintain a
privileged position in both modern and traditional medicines. In recent years, there have …

Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

L Caputi, J Franke, SC Farrow, K Chung, RME Payne… - Science, 2018 - science.org
Vinblastine, a potent anticancer drug, is produced by Catharanthus roseus (Madagascar
periwinkle) in small quantities, and heterologous reconstitution of vinblastine biosynthesis …

Adaptive mechanisms of plant specialized metabolism connecting chemistry to function

JK Weng, JH Lynch, JO Matos, N Dudareva - Nature Chemical Biology, 2021 - nature.com
As sessile organisms, plants evolved elaborate metabolic systems that produce a plethora of
specialized metabolites as a means to survive challenging terrestrial environments …

Subcellular compartmentalization in the biosynthesis and engineering of plant natural produces

L Yao, X Wu, X Jiang, M Shan, Z Zhang, Y Li… - Biotechnology …, 2023 - Elsevier
Plant natural products (PNPs) are specialized metabolites with diverse bioactivities. They
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …

Export of defensive glucosinolates is key for their accumulation in seeds

D Xu, NCH Sanden, LL Hansen, ZM Belew… - Nature, 2023 - nature.com
Plant membrane transporters controlling metabolite distribution contribute key agronomic
traits,,,,–. To eliminate anti-nutritional factors in edible parts of crops, the mutation of …

Substrate (un) specificity of Arabidopsis NRT1/PTR FAMILY (NPF) proteins

C Corratgé-Faillie, B Lacombe - Journal of Experimental Botany, 2017 - academic.oup.com
The conventional approach to categorizing transporters has been to class them according to
their sequence homology, defining a 'family'(or a 'superfamily'if they are numerous), and …