This article gives an overview of recent x-ray diffraction experiments with time resolutions
down to 10− 13 s. The scientific motivation behind the development is outlined, using …

Recent 3-D structures of several intermediates in the photocycle of bacteriorhodopsin (bR)
provide a detailed structural picture of this molecular proton pump in action. In this review …

A molecular description of oxygen and peroxide activation in biological systems is difficult,
because electrons liberated during X-ray data collection reduce the active centres of redox …

Protein motions are essential for function. Comparing protein processes with the dielectric
fluctuations of the surrounding solvent shows that they fall into two classes: nonslaved and …

We report picosecond time-resolved x-ray diffraction from the myoglobin (Mb) mutant in
which Leu29 is replaced by Phe (L29Fmutant). The frame-by-frame structural evolution …

Nitric oxide (NO) has been implicated as mediator in a variety of physiological functions,
including neurotransmission, platelet aggregation, macrophage function, and vasodilation …

The concept that proteins exist in numerous different conformations or conformational
substates, described by an energy landscape, is now accepted, but the dynamics is …

We have used x-ray crystallography to determine the structures of sperm whale myoglobin
(Mb) in four different ligation states (unligated, ferric aquomet, oxygenated, and …

The biological activity of macromolecules is accompanied by rapid structural changes. The
photosensitivity of the carbon monoxide complex of myoglobin was used at the European …

Abstract Background: The hydrogenase of Desulfovibrio sp. catalyzes the reversible
oxidoreduction of molecular hydrogen, in conjunction with a specific electron acceptor …