Secretion of cellular components across the plasma membrane is an essential process that
enables organisms to interact with their environments. Production of extracellular vesicles in …

Outer membrane vesicles (OMVs) are produced by Gram-negative bacteria both in vitro and
in vivo. OMVs are nano-sized spherical vehicles formed by lipid bilayer membranes and …

The continued evolution of biomedical nanotechnology has enabled clinicians to better
detect, prevent, manage, and treat human disease. In order to further push the limits of …

Background Gonorrhoea is a major global public health problem that is exacerbated by drug
resistance. Effective vaccine development has been unsuccessful, but surveillance data …

Neisseria meningitidis is a major cause of bacterial meningitis and septicaemia worldwide
and is associated with high case fatality rates and serious life-long complications among …

Abstract Outer Membrane Vesicles (OMV) have received increased attention in recent years
as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis …

Outer membrane vesicles (OMVs) are released spontaneously during growth by many Gram‐
negative bacteria. They present a range of surface antigens in a native conformation and …

Neisseria meningitidis is the main cause of meningitis and sepsis, potentially life-threatening
conditions. Thanks to advancements in vaccine development, vaccines are now available …

ABSTRACT Introduction: The 2015 Global Meningococcal Initiative (GMI) meeting discussed
the global importance of meningococcal disease (MD) and its continually changing …

ABSTRACT Introduction: The 2018 Global Meningococcal Initiative (GMI) meeting focused
on evolving invasive meningococcal disease (IMD) epidemiology, surveillance, and …