Adversity experienced during gestation is a predictor of lifetime neuropsychiatric disease
susceptibility. Specifically, maternal stress during pregnancy predisposes offspring to sex …

Preterm birth (PTB) is the leading cause of childhood mortality in children under 5 and
accounts for approximately 11% of births worldwide. Premature babies are at risk of a …

Accumulating evidence suggests that human parturition represents an inflammatory
process. Leukocytes are known to infiltrate uterine tissues but the exact timing, nature and …

Increasing epidemiological and experimental evidence implicates gestational infections as
one important factor involved in the pathogenesis of several neuropsychiatric disorders …

Disturbance to early brain development is implicated in several neuropsychiatric disorders
including autism, schizophrenia, and mental retardation. Epidemiological studies have …

The elaboration of cytokines, chemokines and immunomodulatory proteins in the placenta
and gestational membranes has been extensively investigated in the context of both normal …

Cellular senescence, a permanent state of cell cycle arrest accompanied by a complex
phenotype, is an essential mechanism that limits tumorigenesis and tissue damage. In …

Preeclampsia (PE) is an important, common, and dangerous complication of pregnancy; it
causes maternal and perinatal illness and is responsible for a high proportion of maternal …

Objective Although a higher maternal body mass index is associated with preterm birth, it is
unclear whether excess gestational weight gain (GWG) or obesity drives increased risk. We …

Intra-amniotic infection and inflammation are major causes of preterm birth (PTB). However,
intra-amniotic inflammation is often detected in the absence of infection. This may partly be …