As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and
mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to …

The study of tropical diseases like leishmaniasis, a parasitic disease, has not received much
attention even though it is the second-largest infectious disease after malaria. As per the …

Many vaccine candidates against visceral leishmaniasis (VL) have been proposed;
however, to date, none of them have been efficacious for the human or canine disease. On …

Leishmania braziliensis is the main causative agent of Tegumentary Leishmaniasis in the
Americas. However, difficulties related to genome manipulation, experimental infection, and …

The expression of programmed cell death protein-1 (PD-1) and its ligands-PD-L1 and PD-L2-
on T cells and macrophages', respectively, increases in Leishmania infection. The PD-1/PD …

Leishmaniasis are Neglected Tropical Diseases affecting millions of people every year in at
least 98 countries and is one of the major unsolved world health issues. Leishmania is a …

Leishmaniases are severe vector-borne diseases affecting humans and animals, caused by
Leishmania protozoans. Over one billion people and millions of dogs live in endemic areas …

Leishmania infantum parasites cause a severe form of visceral leishmaniasis in human and
viscerocutaneous leishmaniasis in dogs. Recently, we reported that immunization with an …

Leishmaniasis represents a complex of diseases with a broad clinical spectrum and
epidemiological diversity, considered a major public health problem. Although there is …

Leishmania species are causative agents of human leishmaniasis, affecting 12 million
people annually. Drugs available for leishmaniasis are toxic, and no vaccine is available …