Neural tube closure has been studied for many decades, across a range of vertebrates, as a
paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the …

The penultimate effectors of the Hippo signaling pathways YAP and TAZ, are transcriptional
co-activator proteins that play key roles in many diverse biological processes, ranging from …

The Hippo pathway is a universal governor of organ size, tissue homeostasis, and
regeneration. A growing body of work has advanced our understanding of Hippo pathway …

The Warburg effect is one of the metabolic hallmarks of cancer cells, characterized by
enhanced glycolysis even under aerobic conditions. This physiological adaptation is …

During development, progenitors progress through transition states. The cardiac epicardium
contains progenitors of essential non-cardiomyocytes. The Hippo pathway, a kinase …

Although understanding how soluble cues direct cellular processes revolutionised the study
of cell biology in the second half of the 20th century, over the last two decades, new insights …

The stem cells that safeguard synovial joints in adulthood are undefined. Studies on
mesenchymal stromal/stem cells (MSCs) have mainly focused on bone marrow. Here we …

Embryonic induction is a key mechanism in development that corresponds to an interaction
between a signalling and a responding tissue, causing a change in the direction of …

Neural progenitor cells (NPCs) are a promising cell source to repair damaged nervous
tissue. However, expansion of therapeutically relevant numbers of NPCs and their efficient …

Spinal cord injury (SCI) is one of the most challenging clinical issues. It is characterized by
the disruption of neural circuitry and connectivity, resulting in neurological disability. Adipose …