Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

Cancer stem cells (CSCs) represent a subpopulation of tumor cells that possess self‐
renewal and tumor initiation capacity and the ability to give rise to the heterogenous …

Recently, the interplay between autophagy and apoptosis has become an important factor in
chemotherapy for cancer treatment. Inhibition of autophagy may be an effective strategy to …

Background Mitophagy refers to the selective self‐elimination of mitochondria under
damaged or certain developmental conditions. As an important regulatory mechanism to …

Cancer stem cells (CSCs) are a small subpopulation of cells within a tumor that can both self‐
renew and differentiate into other cell types forming the heterogeneous tumor bulk. Since …

Breast cancer tissue contains a small population of cells that have the ability to self-renew;
these cells are known as cancer stem-like cells (CSCs). We have recently shown that …

Breast cancer (BC) is the most frequent cancer among women worldwide and is the leading
cause of cancer-related deaths in women. Cancer cells with stem cell-like features and …

Salinomycin, traditionally used as an anti-coccidial drug, has recently been shown to
possess anti-cancer and anti-cancer stem cell (CSC) effects, as well as activities to …

Ovarian cancer is one of the most important malignancies, and the origin, detection, and
pathogenesis of epithelial ovarian cancer remain elusive. Although many cancer drugs have …