[HTML][HTML] Astrocytes in neurodegeneration: inspiration from genetics
J Huang, C Li, H Shang - Frontiers in neuroscience, 2022 - frontiersin.org
Despite the discovery of numerous molecules and pathologies, the pathophysiology of
various neurodegenerative diseases remains unknown. Genetics participates in the …
various neurodegenerative diseases remains unknown. Genetics participates in the …
[HTML][HTML] The diverse roles of reactive astrocytes in the pathogenesis of amyotrophic lateral sclerosis
K Yang, Y Liu, M Zhang - Brain Sciences, 2024 - mdpi.com
Astrocytes displaying reactive phenotypes are characterized by their ability to remodel
morphologically, molecularly, and functionally in response to pathological stimuli. This …
morphologically, molecularly, and functionally in response to pathological stimuli. This …
[HTML][HTML] Micro-RNAs shuttled by extracellular vesicles secreted from mesenchymal stem cells dampen astrocyte pathological activation and support neuroprotection in …
F Provenzano, S Nyberg, D Giunti, C Torazza, B Parodi… - Cells, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with no effective cure.
Astrocytes display a toxic phenotype in ALS and contribute to motoneuron (MN) …
Astrocytes display a toxic phenotype in ALS and contribute to motoneuron (MN) …
[HTML][HTML] Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes
C Torazza, F Provenzano, E Gallia, M Cerminara… - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
progressive degeneration of motor neurons (MNs). Astrocytes display a toxic phenotype in …
progressive degeneration of motor neurons (MNs). Astrocytes display a toxic phenotype in …
[HTML][HTML] Fundamental role of pentose phosphate pathway within the endoplasmic reticulum in glutamine addiction of triple-negative breast cancer cells
Cancer utilization of large glutamine equivalents contributes to diverging glucose-6-P flux
toward the pentose phosphate shunt (PPP) to feed the building blocks and the antioxidant …
toward the pentose phosphate shunt (PPP) to feed the building blocks and the antioxidant …
[HTML][HTML] Opportunistic skeletal muscle metrics as prognostic tools in metastatic castration-resistant prostate cancer patients candidates to receive Radium-223
M Bauckneht, R Lai, F D'Amico, A Miceli… - Annals of Nuclear …, 2022 - Springer
Objective Androgen deprivation therapy alters body composition promoting a significant loss
in skeletal muscle (SM) mass through inflammation and oxidative damage. We verified …
in skeletal muscle (SM) mass through inflammation and oxidative damage. We verified …
[HTML][HTML] Nuclear medicine preclinical research: the role of cell cultures
M Busk, S Sinning, AKO Alstrup, OL Munk… - Seminars in Nuclear …, 2023 - Elsevier
Cell lines are essential in biomedical research due to their adaptability and precise
simulation of physiological and pathophysiological conditions. Cell culture techniques have …
simulation of physiological and pathophysiological conditions. Cell culture techniques have …
[PDF][PDF] Kerlero de Rosbo, N
F Provenzano, S Nyberg, D Giunti, C Torazza… - Milanese, M, 2022 - academia.edu
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with no effective cure.
Astrocytes display a toxic phenotype in ALS and contribute to motoneuron (MN) …
Astrocytes display a toxic phenotype in ALS and contribute to motoneuron (MN) …
[HTML][HTML] AMPKα1 Deficiency in Astrocytes from a Rat Model of ALS Is Associated with an Altered Metabolic Resilience
I Belo do Nascimento, G Ates, N Desmet, P Beckers… - Biomolecules, 2023 - mdpi.com
Alterations in the activity of the regulator of cell metabolism AMP-activated protein kinase
(AMPK) have been reported in motor neurons from patients and animal models of …
(AMPK) have been reported in motor neurons from patients and animal models of …
Potential of neuroimaging as a biomarker in amyotrophic lateral sclerosis: from structure to metabolism
W Sun, SH Liu, XJ Wei, H Sun, ZW Ma, XF Yu - Journal of Neurology, 2024 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by motor neuron degeneration. The development of ALS involves metabolite …
characterized by motor neuron degeneration. The development of ALS involves metabolite …