[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies

L Liu, PG Kshirsagar, SK Gautam, M Gulati, EI Wafa… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

Degradable polymeric bio (nano) materials and their biomedical applications: A comprehensive overview and recent updates

K Kuperkar, LI Atanase, A Bahadur, IC Crivei… - Polymers, 2024 - mdpi.com
Degradable polymers (both biomacromolecules and several synthetic polymers) for
biomedical applications have been promising very much in the recent past due to their low …

Polymeric nanoparticles in brain cancer therapy: A review of current approaches

CA Caraway, H Gaitsch, EE Wicks, A Kalluri, N Kunadi… - Polymers, 2022 - mdpi.com
Translation of novel therapies for brain cancer into clinical practice is of the utmost
importance as primary brain tumors are responsible for more than 200,000 deaths …

Pharmacology of apocynin: a natural acetophenone

SR Savla, AP Laddha, YA Kulkarni - Drug metabolism reviews, 2021 - Taylor & Francis
Apocynin is a naturally occurring acetophenone, found in the roots of Apocynum
cannabinum and Picrorhiza kurroa. Various chemical and pharmaceutical modifications …

Neurodegenerative disorders management: state-of-art and prospects of nano-biotechnology

R Kumar, KR Aadil, K Mondal, YK Mishra… - Critical Reviews in …, 2022 - Taylor & Francis
Neurodegenerative disorders (NDs) are highly prevalent among the aging population. It
affects primarily the central nervous system (CNS) but the effects are also observed in the …

Nanotechnology to improve the Alzheimer's disease therapy with natural compounds

MJ Ramalho, S Andrade, JA Loureiro… - Drug delivery and …, 2020 - Springer
Alzheimer's disease (AD) is a form of dementia with high impact worldwide, accounting with
more than 46 million cases. It is estimated that the number of patients will be four times …

Journey to the market: the evolution of biodegradable drug delivery systems

M Zhu, AK Whittaker, FY Han, MT Smith - Applied Sciences, 2022 - mdpi.com
Biodegradable polymers have been used as carriers in drug delivery systems for more than
four decades. Early work used crude natural materials for particle fabrication, whereas more …

110th Anniversary: Nanoparticle Mediated Drug Delivery for the Treatment of Alzheimer's Disease: Crossing the Blood–Brain Barrier

ME Wechsler, JE Vela Ramirez… - Industrial & engineering …, 2019 - ACS Publications
Alzheimer's disease is an irreversible neurodegenerative disorder affecting approximately 6
million Americans, 90% of which are over the age of 65. The hallmarks of the disease are …

Nanoparticle approaches for the renin-angiotensin system

SD Hettiarachchi, YM Kwon, Y Omidi, RC Speth - Heliyon, 2023 - cell.com
The renin-angiotensin system (RAS) is a hormonal cascade that contributes to several
disorders: systemic hypertension, heart failure, kidney disease, and neurodegenerative …

Functionalized polyanhydride nanoparticles for improved treatment of mitochondrial dysfunction

BW Schlichtmann, B Kalyanaraman… - … Research Part B …, 2022 - Wiley Online Library
Parkinson's disease (PD) is a devastating neurodegenerative disease affecting a large
proportion of older adults. Exposure to pesticides like rotenone is a leading cause for PD. To …