In recent years, several drugs have been developed deriving from traditional products and
current drug research is actively investigating the possible therapeutic roles of many …

Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Turmeric (Curcuma longa) and its constituent, curcumin, have been used for their
therapeutic properties for a long time. Most of the medicinal impacts of turmeric and …

Introduction Curcuma longa, popularly known as Turmeric, is a rhizomatous herbaceous
perennial plant used in folk medicine for the treatment, prevention, and management of …

It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …

TNFs are major mediators of inflammation and inflammation‐related diseases, hence, the U
nited S tates F ood and D rug A dministration (FDA) has approved the use of blockers of the …

Methotrexate (MTX), an antineoplastic and immunosuppressive drug, widely used in the
treatment of different types of cancers and the management of chronic inflammatory …

Aim Rheumatoid arthritis (RA) is a systemic inflammatory disease. In recent years, new
drugs with novel targets have been developed to increase the efficacy of drugs in the …

Background Prednisolone (PD) is extremely effective for treating rheumatoid arthritis (RA).
However, it distributes nonspecifically throughout the body and its use is associated with …

Combination of drugs is extensively used to treat chronic inflammatory disease. Naringin
(NAR), sulforaphane (SFN), and phenethyl isothiocyanate (PEITC) are nutraceuticals with …