Monitoring host–pathogen interactions using chemical proteomics

AW Muñoz, W Zhao, SA Sieber - RSC Chemical Biology, 2024 - pubs.rsc.org
With the rapid emergence and the dissemination of microbial resistance to conventional
chemotherapy, the shortage of novel antimicrobial drugs has raised a global health threat …

[HTML][HTML] Chemical biology tools to probe bacterial glycans

D Calles-Garcia, DH Dube - Current opinion in chemical biology, 2024 - Elsevier
Bacterial cells are covered by a complex carbohydrate coat of armor that allows bacteria to
thrive in a range of environments. As a testament to the importance of bacterial glycans …

Azide-masked fluorescence turn-on probe for imaging mycobacteria

SH Liyanage, NGH Raviranga, JG Ryan, SS Shell… - JACS Au, 2023 - ACS Publications
A fluorescence turn-on probe, an azide-masked and trehalose-derivatized carbazole (Tre-
Cz), was developed to image mycobacteria. The fluorescence turn-on is achieved by …

Azido inositol probes enable metabolic labeling of inositol-containing glycans and reveal an inositol importer in mycobacteria

H Hodges, K Obeng, C Avanzi, AP Ausmus… - ACS chemical …, 2023 - ACS Publications
Bacteria from the genus Mycobacterium include pathogens that cause serious diseases in
humans and remain as difficult infectious agents to treat. Central to these challenges are the …

Fluorogenic Probes of the Mycobacterial Membrane as Reporters of Antibiotic Action

MG Wuo, CL Dulberger, TC Warner… - Journal of the …, 2024 - ACS Publications
The genus Mycobacterium includes species such as Mycobacterium tuberculosis, which can
cause deadly human diseases. These bacteria have a protective cell envelope that can be …

Chemical approaches to unraveling the biology of mycobacteria

P Finin, RMN Khan, S Oh, HIM Boshoff, CE Barry - Cell chemical biology, 2023 - cell.com
Mycobacterium tuberculosis (Mtb), perhaps more than any other organism, is intrinsically
appealing to chemical biologists. Not only does the cell envelope feature one of the most …

[HTML][HTML] Synthesis of trehalose-based chemical tools for the study of the mycobacterial membrane

E Lesur, P Rollando… - Comptes …, 2023 - comptes-rendus.academie-sciences …
Corynebacteriales including the causative agent of many diseases such as tuberculosis are
known to be extremely resistant against external stress as well as to antibiotic treatments …

[PDF][PDF] Chemical Biology

AW Munoz, W Zhao, SA Sieber - 2024 - pdfs.semanticscholar.org
With the rapid emergence and the dissemination of microbial resistance to conventional
chemotherapy, the shortage of novel antimicrobial drugs has raised a global health threat …

The right tool for the job: Chemical biology and microbiome science

C Whidbey - Cell Chemical Biology, 2025 - cell.com
Microbiomes exist in ecological niches ranging from the ocean and soil to inside of larger
organisms like plants and animals. Within these niches, microbes play key roles in …