Subclinical inflammation has been associated with psychosis; however, it remains unknown
whether this phenomenon appears also in the premorbid phase. Therefore, we performed a …

Background Studies linking neuro-inflammation to psychotic episodes has been rapidly
expanding. Assessments of changes in inflammatory biomarkers in prodromal patients who …

Immune parameters are elevated in psychosis, but it is unclear whether alterations are
homogenous across patients or heterogeneity exists, consistent with the hypothesis that …

Immunological/inflammatory factors are implicated in the development of psychosis.
Complement is a key driver of inflammation; however, it remains unknown which factor is …

Background Immune dysregulation has been observed in patients with schizophrenia or first-
episode psychosis, but few have examined dysregulation in those at clinical high-risk (CHR) …

Objective Schizophrenia is a disabling disorder of unknown aetiology, lacking definite
diagnostic method and cure. A reliable biological marker of schizophrenia is highly …

There is strong evidence that sleep disturbances are commonly experienced by people with
psychosis. Evidence has also shown that sleep disturbances are present since the very …

Background With a complex etiology and chronic, disabling evolution, schizophrenia
continues to represent a challenge for patients, clinicians, and researchers alike. Recent …

Introduction Research examining the role of inflammation in psychosis has produced
inconsistent results. Variables that influence inflammation, including antipsychotic …

Introduction: Immune alterations are associated with the progression of psychosis. However,
there are few studies designed to longitudinally measure inflammatory biomarkers during …