Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Transforming growth factor-β (TGFβ) isoforms are upregulated and activated in myocardial
diseases and have an important role in cardiac repair and remodelling, regulating the …

The molecular pathology of multi-organ injuries in COVID-19 patients remains unclear,
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …

The members of the transforming growth factor β (TGF-β) superfamily are essential
regulators of cell differentiation, phenotype and function, and have been implicated in the …

Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries
characterized by a local accumulation of cholesterol and non-resolving inflammation …

Left ventricular non-compaction, the most recently classified form of cardiomyopathy, is
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …

Atherosclerosis contributes to the development of many cardiovascular diseases, which
remain the leading cause of death in developed countries. Atherosclerosis is a chronic …

Keloids, fibroproliferative dermal tumors with effusive accumulation of extracellular matrix
(ECM) components, particularly collagen, result from excessive expression of growth factors …

Myocardial TGF-β expression is upregulated in experimental models of myocardial infarction
and cardiac hypertrophy, and in patients with dilated or hypertrophic cardiomyopathy …

The cardiovascular system ensures the delivery of nutrients, oxygen, and blood and immune
cells to all organs and tissues: it is also responsible for the removal of waste metabolites …