New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …

The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

The gut microbiota plays a crucial role in human health and disease. Gut dysbiosis is known
to be associated with increased susceptibility to respiratory diseases and modifications in …

Macrophages are tissue‐resident myeloid cells with essential roles in host defense, tissue
repair, and organ homeostasis. The lung harbors a large number of macrophages that …

The lungs present a challenging immunological dilemma for the host. Anatomically
positioned at the environmental interface, they are constantly exposed to antigens …

Background Alterations in the respiratory microbiome are common in chronic lung diseases,
correlate with decreased lung function, and have been associated with disease progression …

The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

Once thought to be sterile, the human lung is now well recognized to harbor a consortium of
microorganisms collectively known as the lung microbiome. The lung microbiome is altered …

Background The lung microbiome maintains the homeostasis of the immune system within
the lungs. In acute respiratory distress syndrome (ARDS), the lung microbiome is enriched …

Bronchoalveolar lavage (BAL) is a key clinical and research tool in lung transplantation
(LTx). However, BAL collection and processing are not standardized across LTx centers …