Topical treatment modalities have multiple advantages starting with the convenient
application and non-invasive treatment and ending with the reduction of the risk of the …

Adapalene (ADA) is primarily used as a cosmeceutical gel in the treatment of mild-moderate
acne and is also used off-label to treat keratosis pilaris as well as other skin conditions. A …

Owing to its high sensitivity and specificity, fluorescence spectroscopy has emerged as a
critical analytical tool for pharmaceutical formulations. Over the last three decades, it has …

Intrinsic fluorescence of drugs brings valuable information on their localization in the
organism and their interaction with key biomolecules. In this work, we investigate the …

Adapalene (ADAP) is an important drug widely used in the topical treatment of acne. It is a
third-generation retinoid and provides keratolytic, anti-inflammatory, and antiseborrhoic …

This study is concerned with two sensitive, fast and reproducible approaches; namely,
second-derivative synchronous fluorimetry (method I) and reversed phase high-performance …

A highly sensitive, simple, accurate, and precise high-performance thin-layer
chromatographic (HPTLC) method was developed and validated for the quantitative …

A simple and inexpensive method was developed with high performance liquid
chromatography with PDA detection for determination of Adapalene and related impurities …

Lifestyles and environmental changes draw people away from healthy and natural-looking
skin. To hide the impaired and damaged skin texture as a result of several factors, people …

A new high-performance thin-layer chromatography (HPTLC) method for the determination
of adapalene and phenoxyethanol was developed and validated. An excellent resolution …