The string graph for a collection of next-generation reads is a lossless data representation that is fundamental for de novo assemblers based on the overlap-layout-consensus …
T Beller, E Ohlebusch - Algorithms for Molecular Biology, 2016 - Springer
Abstract Background Recently, Marcus et al.(Bioinformatics 30: 3476–83, 2014) proposed to use a compressed de Bruijn graph to describe the relationship between the genomes of …
The large amount of short read data that has to be assembled in future applications, such as in metagenomics or cancer genomics, strongly motivates the investigation of disk-based …
Some recent results (Bauer et al. in Algorithms in bioinformatics, Springer, Berlin, pp 326– 337, 2012; Cox et al. in Algorithms in bioinformatics, Springer, Berlin, pp. 214–224, 2012; …
Converting a set of sequencing reads into a lossless compact data structure that encodes all the relevant biological information is a major challenge. The classical approaches are to …
Converting a set of sequencing reads into a lossless compact data structure that encodes all the relevant biological information is a major challenge. The classical approaches are to …
Indexing of very large collections of strings such as those produced by the widespread sequencing technologies, heavily relies on multi-string generalizations of the Burrows …
The string graph for a collection of next-generation reads is a lossless data representation that is fundamental for de novo assemblers based on the overlap-layout-consensus …
For at least three decades computer science approaches have proved to be of utmost importance for extrapolating knowledge from biological data. Indeed, the amount of data …