Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

During the last century, there has been an increasing prevalence of hyperuricaemia noted in
many populations. While uric acid is usually discussed in the context of gout …

Background Elevated serum urate levels are associated with progression of chronic kidney
disease. Whether urate-lowering treatment with allopurinol can attenuate the decline of the …

Gout is a crystal-deposition disease that results from chronic elevation of uric acid levels
above the saturation point for monosodium urate (MSU) crystal formation. Initial presentation …

Rationale & Objective Epidemiologic and clinical studies have suggested that urate-
lowering therapy may slow the progression of chronic kidney disease (CKD). However …

The association between uric acid (UA) on one side and systemic hypertension (Htn),
dyslipidemia, glucose intolerance, overweight, fatty liver, renal disease and cardiovascular …

Substantial evidence suggests that chronic hyperuricemia is an independent risk factor for
hypertension, metabolic syndrome, chronic kidney disease (CKD) and cardiovascular …

Chronic kidney disease has become a serious public health issue. There are currently over
1.4 million patients receiving renal replacement therapy worldwide. One way to reduce the …

Aims To compare the occurrence of cerebral, cardiovascular, and renal events in patients
with hyperuricaemia treated with febuxostat and those treated with conventional therapy with …

Elevated serum uric acid concentration is a common laboratory finding in subjects with
metabolic syndrome/obesity, hypertension, kidney disease and cardiovascular events …