Neisseria gonorrhoeae (Gc) is a human-specific pathogen that causes the sexually
transmitted infection gonorrhea. Gc survives in neutrophil-rich gonorrheal secretions, and …

Neisseria gonorrhoeae infection is characterized by local and abundant recruitment of
neutrophils. Despite neutrophils' antimicrobial activities, viable N. gonorrhoeae is recovered …

Clustered regularly interspaced short palindromic repeats (CRISPR) are prokaryotic
adaptive immune systems regularly utilized as DNA-editing tools. While Neisseria …

Abstract CR3 (CD11b/CD18; αmβ2 integrin) is a conserved phagocytic receptor. The active
conformation of CR3 binds the iC3b fragment of complement C3 as well as many host and …

The bacterial pathogen Neisseria gonorrhoeae is an urgent global health problem due to
increasing numbers of infections, coupled with rampant antibiotic resistance. Vaccines …

Gonorrhea, caused by the bacterium Neisseria gonorrhoeae (Gc), is characterized by
neutrophilic influx to infection sites. Gc has developed mechanisms to resist killing by …

Here we report the structure of Opa60 in lipid bilayers using proton-detected magic-angle
spinning nuclear magnetic resonance (MAS NMR). Preparations including near-native …

Helicobacter pylori is gastric pathogen that colonizes 50% of the global population and
evokes a histological gastritis that often remains asymptomatic. This infection is …

Chlamydia and gonorrhea (CTNG) are sexually transmitted infections (STIs) that can lead to
complications in males and females. If a pregnant individual is infected with CTNG, they risk …

I would like to thank Dr. Loren Andreas for giving me the opportunity to write this thesis and
for his supervision, his willingness to always lend an ear to my questions and his constant …