The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …

Emerging therapeutics that utilize RNA interference (RNAi) have the potential to treat broad
classes of diseases due to their ability to reversibly silence target genes. In August 2018, the …

Targeting tumors with long-circulating nano-scaled carriers is a promising strategy for
systemic cancer treatment. Compared with free small therapeutic agents, nanocarriers can …

A poly (ethylene glycol)(PEG) macromolecular chain transfer agent (macro-CTA) is prepared
in high yield (> 95%) with 97% dithiobenzoate chain-end functionality in a three-step …

Polypeptides derived from naturally occurring α-amino acids have emerged as a unique and
versatile family of bio-inspired biomaterials that can be tailor-made for varying biomedical …

Written at a level comprehensible to non-experts, this handbook covers the current state of
encapsulation and controlled released technologies, presenting the fundamental processes …

The progress in NCA polymerisation combined with advanced orthogonal functionalization
techniques as well as the integration with other controlled polymerisation techniques …

Biological interactions between tumor-associated macrophages (TAMs), cancer cells and
other cells within the tumor microenvironment contribute to tumorigenesis, tumor growth …