Drugs encapsulation is a suitable strategy in order to cope with the limitations of
conventional dosage forms such as unsuitable bioavailability, stability, taste, and odor …

The blood-brain barrier and the blood-cerebrospinal fluid barrier are major obstacles in
central nervous system (CNS) drug delivery, since they block most molecules from entering …

Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Recently, owing to well-controlled release, enhanced distribution and increased
permeability, nanocarriers used for alternative drug and food-delivery strategies have …

Highlights•Doxorubicin (DOX) is considered one of the most effective chemotherapeutic
agents.•Dose-cumulative cardiotoxicity is the most dangerous adverse effect.•DOX-based …

Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …

The blood–brain barrier (BBB) is composed of brain endothelial cells, pericytes, and
astrocytes, which build a tight cellular barrier. Therapeutic (macro) molecules are not able to …

In this review article we discuss some of the key aspects concerning the development of a
polymer-based nanoparticle formulation for intravenous drug delivery. Since numerous …

Nanocarriers (NCs) are a type of drug delivery system commonly used to regulate the
pharmacokinetic and pharmacodynamic properties of drugs. Although a wide variety of NCs …

Nanoengineered drug delivery systems (nDDS) have been successfully used as clinical
tools for not only modulation of pharmacological drug release profile but also specific …