[HTML][HTML] Mechanisms of action of trans fatty acids

AB Oteng, S Kersten - Advances in nutrition, 2020 - Elsevier
Human studies have established a positive association between the intake of industrial trans
fatty acids and the development of cardiovascular diseases, leading several countries to …

Sheep and goats respond differently to feeding strategies directed to improve the fatty acid profile of milk fat

A Nudda, A Cannas, F Correddu, AS Atzori, MF Lunesu… - Animals, 2020 - mdpi.com
Simple Summary Sheep and goat milk, as well as dairy products, are considered good
sources of high-quality nutrients, particularly proteins and fats. Many positive effects on …

Eighteen‑carbon trans fatty acids and inflammation in the context of atherosclerosis

CA Valenzuela, EJ Baker, EA Miles, PC Calder - Progress in lipid research, 2019 - Elsevier
Endothelial dysfunction is a pro-inflammatory state characterized by chronic activation of the
endothelium, which leads to atherosclerosis and cardiovascular disease (CVD). Intake of …

Impact of dietary fat on the progression of liver fibrosis: lessons from animal and cell studies

F Jia, X Hu, T Kimura, N Tanaka - International journal of molecular …, 2021 - mdpi.com
Previous studies have revealed that a high-fat diet is one of the key contributors to the
progression of liver fibrosis, and increasing studies are devoted to analyzing the different …

Trans Fatty Acids Suppress TNF-α-Induced Inflammatory Gene Expression in Endothelial (HUVEC) and Hepatocellular Carcinoma (HepG2) Cells

MS Da Silva, P Julien, JF Bilodeau, O Barbier… - Lipids, 2017 - Springer
Trans fatty acids (TFA) intake has been linked to cardiovascular diseases and liver diseases;
yet the effect of TFA on inflammation remains controversial. Accordingly, the objective of this …

Variations in HDL-carried miR-223 and miR-135a concentrations after consumption of dietary trans fat are associated with changes in blood lipid and inflammatory …

V Desgagné, SP Guay, R Guérin, F Corbin… - Epigenetics, 2016 - Taylor & Francis
ABSTRACT A high consumption of trans fatty acids (TFAs) is associated with an increased
risk of cardiovascular diseases (CVDs). High-density lipoproteins (HDLs) have many …

Comparing the lipogenic and cholesterolgenic effects of individual trans‐18:1 isomers in liver cells

P Vahmani, WJ Meadus, P Duff… - European Journal of …, 2017 - Wiley Online Library
The present study compared the lipogenic/cholesterolgenic effects of t6‐, t9‐(positive
control), t10‐, t11‐, t13‐, t14‐, t15‐18: 1, cis (c) 9‐18: 1 (cis control) or bovine serum albumin …

Different metabolism and toxicity of TRANS fatty acids, elaidate and vaccenate compared to cis-oleate in HepG2 cells

F Sarnyai, É Kereszturi, K Szirmai, J Mátyási… - International Journal of …, 2022 - mdpi.com
Trans fatty acids (TFAs) are not synthesized in the human body but are generally ingested in
substantial amounts. The widespread view that TFAs, particularly those of industrial origin …

Changes in high-density lipoprotein-carried miRNA contribution to the plasmatic pool after consumption of dietary trans fat in healthy men

V Desgagné, R Guérin, SP Guay, F Corbin… - …, 2017 - Taylor & Francis
Aim: High-density lipoproteins (HDLs) are associated to cardioprotection and transport
functional miRNAs in circulation. The aim of this study is to assess whether consumption of …

Differential Effects of Ruminant and Industrial 18-Carbon trans-Monounsaturated Fatty Acids (trans Vaccenic and Elaidic) on the Inflammatory Responses of an …

CA Valenzuela, EJ Baker, CO De Souza, EA Miles… - Molecules, 2021 - mdpi.com
Endothelial dysfunction and inflammation are recognised factors in the development of
atherosclerosis. Evidence suggests that intake of industrial trans fatty acids (TFAs) promotes …