The emerging role of MicroRNAs in bone diseases and their therapeutic potential
LA Bravo Vázquez, MY Moreno Becerril… - Molecules, 2021 - mdpi.com
MicroRNAs (miRNAs) are a class of small (20–24 nucleotides), highly conserved, non-
coding RNA molecules whose main function is the post-transcriptional regulation of gene …
coding RNA molecules whose main function is the post-transcriptional regulation of gene …
[HTML][HTML] The involvement of microRNAs in Bone Remodeling Signaling pathways and their role in the development of osteoporosis
RF Jiménez-Ortega, AI Ortega-Meléndez, N Patiño… - Biology, 2024 - mdpi.com
Simple Summary Osteoporosis is a disease that is characterized by bone mass loss and
microarchitecture deterioration, due to alterations in the bone remodeling mechanism, which …
microarchitecture deterioration, due to alterations in the bone remodeling mechanism, which …
LncRNA SNHG14 activates autophagy via regulating miR-493-5p/Mef2c axis to alleviate osteoporosis progression
J Xue, L Liu, H Liu, Z Li - Communications Biology, 2023 - nature.com
Osteoporosis is a progressive bone disease caused by impaired function of endogenous
bone marrow-derived mesenchymal stem cells (BMSCs). Herein, we investigated the …
bone marrow-derived mesenchymal stem cells (BMSCs). Herein, we investigated the …
Roles of circular RNAs in osteogenic/osteoclastogenic differentiation
T Wang, C Zhang, L Xu, X Li - Biofactors, 2024 - Wiley Online Library
The process of bone remodeling occurs and is regulated through interactions between
osteoclasts, which resorb bone, and osteoblasts, which generate bone tissue. When the …
osteoclasts, which resorb bone, and osteoblasts, which generate bone tissue. When the …
Pathophysiology and emerging molecular therapeutic targets in heterotopic ossification
F Felix-Ilemhenbhio, GAE Pickering… - International Journal of …, 2022 - mdpi.com
The term heterotopic ossification (HO) describes bone formation in tissues where bone is
normally not present. Musculoskeletal trauma induces signalling events that in turn trigger …
normally not present. Musculoskeletal trauma induces signalling events that in turn trigger …
MiR-21-5p regulates the dynamic of mitochondria network and rejuvenates the senile phenotype of bone marrow stromal cells (BMSCs) isolated from osteoporotic …
M Sikora, A Śmieszek, A Pielok, K Marycz - Stem cell research & therapy, 2023 - Springer
Background Progression of senile osteoporosis is associated with deteriorated regenerative
potential of bone marrow-derived mesenchymal stem/stromal cells (BMSCs). According to …
potential of bone marrow-derived mesenchymal stem/stromal cells (BMSCs). According to …
[HTML][HTML] MCF2L-AS1 promotes the biological behaviors of hepatocellular carcinoma cells by regulating the miR-33a-5p/FGF2 axis
H Ou, Y Qian, L Ma - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Abstract Long noncoding RNA MCF2L-AS1 functions in the development of cancers like
lung cancer, ovarian cancer, and colorectal cancer. Notwithstanding, its function in …
lung cancer, ovarian cancer, and colorectal cancer. Notwithstanding, its function in …
[Retracted] lncRNA NBAT1 Inhibits Cell Metastasis and Promotes Apoptosis in Endometrial Cancer by Sponging miR‐21‐5p to Regulate PTEN
C Tian, J Su, Z Ma, Y Wu, H Ma - … and Mathematical Methods in …, 2022 - Wiley Online Library
Objective. Long noncoding RNA neuroblastoma‐associated transcript 1 (NBAT1) is
implicated in the progression of various cancers. Nevertheless, its biological function in …
implicated in the progression of various cancers. Nevertheless, its biological function in …
The regulatory activities of MALAT1 in the development of bone and cartilage diseases
D Zhang, J Xue, F Peng - Frontiers in Endocrinology, 2022 - frontiersin.org
Long non-coding RNAs (lncRNAs) have been comprehensively implicated in various
cellular functions by mediating transcriptional or post-transcriptional activities. MALAT1 is …
cellular functions by mediating transcriptional or post-transcriptional activities. MALAT1 is …
The potential role of genetics, environmental factors, and gut dysbiosis in the aberrant non-coding RNA expression to mediate inflammation and osteoclastogenic …
HT Liao, CY Tsai, CC Lai, SC Hsieh, YS Sun… - Frontiers in cell and …, 2022 - frontiersin.org
Ankylosing spondylitis (AS) or radiographic axial spondyloarthritis is a chronic immune-
mediated rheumatic disorder characterized by the inflammation in the axial skeleton …
mediated rheumatic disorder characterized by the inflammation in the axial skeleton …