Exposure to outdoor particulate matter air pollution and risk of gastrointestinal cancers in adults: a systematic review and meta-analysis of epidemiologic evidence

N Pritchett, EC Spangler, GM Gray… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Outdoor air pollution is a known lung carcinogen, but research investigating
the association between particulate matter (PM) and gastrointestinal (GI) cancers is limited …

Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

Exposure of human lung cells to polystyrene microplastics significantly retards cell proliferation and triggers morphological changes

KE Goodman, JT Hare, ZI Khamis, T Hua… - Chemical research in …, 2021 - ACS Publications
Microplastics in the environment produced by decomposition of globally increasing waste
plastics have become a dominant component of both water and air pollution. To examine the …

Oxidative stress-induced DNA damage by particulate air pollution

L Risom, P Møller, S Loft - Mutation Research/Fundamental and Molecular …, 2005 - Elsevier
Exposure to ambient air particulate matter (PM) is associated with pulmonary and
cardiovascular diseases and cancer. The mechanisms of PM-induced health effects are …

Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of the In Vivo and In Vitro Studies

A Nemmar, JA Holme, I Rosas… - BioMed research …, 2013 - Wiley Online Library
Epidemiological and clinical studies have linked exposure to particulate matter (PM) to
adverse health effects, which may be registered as increased mortality and morbidity from …

From particles to patients: oxidative stress and the cardiovascular effects of air pollution

MR Miller, CA Shaw, JP Langrish - Future cardiology, 2012 - Taylor & Francis
Air pollution, especially airborne particulate matter (PM), is associated with an increase in
both morbidity and mortality from cardiovascular disease, although the underlying …

Toxicological assessment of ambient and traffic-related particulate matter: a review of recent studies

TMCM De Kok, HAL Driece, JGF Hogervorst… - … Research/Reviews in …, 2006 - Elsevier
Particulate air pollution (PM) is an important environmental health risk factor for many
different diseases. This is indicated by numerous epidemiological studies on associations …

Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: effect of particle composition

A Gojova, B Guo, RS Kota, JC Rutledge… - Environmental …, 2007 - ehp.niehs.nih.gov
Background The mechanisms governing the correlation between exposure to ultrafine
particles and the increased incidence of cardiovascular disease remain unknown. Ultrafine …

Cell cycle alterations induced by urban PM2. 5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved

E Longhin, JA Holme, KB Gutzkow, VM Arlt… - Particle and fibre …, 2013 - Springer
Background This study explores and characterizes cell cycle alterations induced by urban
PM2. 5 in the human epithelial cell line BEAS-2B, and elucidates possible mechanisms …

p38 mitogen-activated protein kinase pathways in asthma and COPD

KF Chung - Chest, 2011 - Elsevier
The mitogen-activated protein kinase (MAPK) family includes the p38 kinases, which consist
of highly conserved proline-directed serine-threonine protein kinases that are activated in …