During pregnancy and lactation, female physiology adapts to meet the added nutritional
demands of fetuses and neonates. An average full-term fetus contains∼ 30 g calcium, 20 g …

▪ Abstract Parathyroid hormone-related protein (PTHrP) is the agent responsible for humoral
hypercalcemia of malignancy. Its pathogenic role in this syndrome is well established, and …

The PTH/PTHrP receptor binds to two ligands with distinct functions: the calcium-regulating
hormone, parathyroid hormone (PTH), and the paracrine factor, PTH-related protein …

Bone development is a multistep process that includes patterning of skeletal elements,
commitment of hematopoietic and/or mesenchymental cells to chondrogenic and osteogenic …

Preimplantation development in mammals involves both the development of the embryo and
the preparation of the uterus in anticipation of blastocyst implantation. Preparation of the …

Introduction Features of hyperparathyroidism have long been associated with malignancy,
and with the advent of sufficiently sensitive bioassays, parathyroid hormone (PTH)-like …

During mammalian embryo development, the correct formation of the first extraembryonic
endoderm lineages is fundamental for successful development. In the periimplantation …

Publisher Summary Much of normal calcium and bone homeostasis in the adult can be
explained by the interactions of parathyroid hormone (PTH), 1, 25-dihydroxyvitamin D …

Parathyroid hormone-related peptide (PTHrP) has been identified as the factor responsible
for the humoral hypercalcemia of malignancy (HHM). Since the cloning of the cDNA, it has …

In this study we describe the spatia-temporal expression of Parathyroid Hormone related
Peptide (PTHrP) mRNA during murine postimplantation development from day 5.5 post …