The role of microRNAs in solving COVID-19 puzzle from infection to therapeutics: A mini-review

S Paul, LAB Vázquez, PR Reyes-Pérez… - Virus Research, 2022 - Elsevier
Nowadays, one of the major global health concerns is coronavirus disease 2019 (COVID-
19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

SARS-CoV-2 variants identification: overview of molecular existing methods

G Berno, L Fabeni, G Matusali, CEM Gruber, M Rueca… - Pathogens, 2022 - mdpi.com
Since the beginning of COVID-19 pandemic the Real Time sharing of genome sequences of
circulating virus supported the diagnostics and surveillance of SARS-CoV-2 and its …

Vaccine design and delivery approaches for COVID-19

K Shahzamani, F Mahmoudian… - International …, 2021 - Elsevier
COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent
times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of …

COVID-19 pandemic: the delta variant, T-cell responses, and the efficacy of developing vaccines

B Biswas, S Chattopadhyay, S Hazra, AK Hansda… - Inflammation …, 2022 - Springer
Background The mayhem COVID-19 that was ushered by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV2) was declared pandemic by the World Health …

[HTML][HTML] Recent advancements in the discovery of small-molecule non-nucleoside inhibitors targeting SARS-CoV-2 RdRp

B Zhou, D Chen, T Zhang, C Song, X Zhang… - Biomedicine & …, 2024 - Elsevier
The RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 plays a pivotal role in the life
cycle of the novel coronavirus and stands as a significant and promising target for anti-SARS …

Antivirals for broader coverage against human coronaviruses

M Outteridge, CM Nunn, K Devine, B Patel, GR McLean - Viruses, 2024 - mdpi.com
Coronaviruses (CoVs) are enveloped positive-sense single-stranded RNA viruses with a
genome that is 27–31 kbases in length. Critical genes include the spike (S), envelope (E) …

Mutations in the receptor-binding domain of human SARS CoV-2 spike protein increases its affinity to bind human ACE-2 receptor

GKRS Naresh, L Guruprasad - Journal of Biomolecular Structure …, 2023 - Taylor & Francis
The severe acute respiratory syndrome virus-2 (SARS CoV-2) infection has resulted in the
current global pandemic. The binding of SARS CoV-2 spike protein receptor-binding domain …

Traceability of SARS‐CoV‐2 transmission through quasispecies analysis

S Messali, A Rondina, M Giovanetti… - Journal of Medical …, 2023 - Wiley Online Library
During COVID‐19 pandemic, consensus genomic sequences were used for rapidly monitor
the spread of the virus worldwide. However, less attention was paid to intrahost genetic …

The impact of demographic, clinical characteristics and the various COVID-19 variant types on all-cause mortality: A case-series retrospective study

F Khamis, S Al Awaidy, M Ba'Omar, W Osman… - Diseases, 2022 - mdpi.com
(1) Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
rapidly evolved into a pandemic affecting virtually every country in the world. We evaluated …

Early mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants in Chile

KY Oróstica, SB Mohr, J Dehning, S Bauer… - Scientific Reports, 2024 - nature.com
Genomic surveillance (GS) programmes were crucial in identifying and quantifying the
mutating patterns of SARS-CoV-2 during the COVID-19 pandemic. In this work, we develop …