L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV- 2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …
SARS‐CoV‐2 is a newly emerged coronavirus that caused the global COVID‐19 outbreak in early 2020. COVID‐19 is primarily associated with lung injury, but many other clinical …
Dear Editor, Omicron (B. 1.1. 529), is a heavily mutated and highly contagious SARS-CoV-2 variant, which is currently causing large outbreaks in many countries. Protection provided by …
L Wettstein, F Kirchhoff, J Münch - International Journal of Molecular …, 2022 - mdpi.com
TMPRSS2 is a type II transmembrane protease with broad expression in epithelial cells of the respiratory and gastrointestinal tract, the prostate, and other organs. Although the …
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the first documented pandemic due to a coronavirus that continues to be a major health …
N Heinen, M Kloehn, E Steinmann, S Pfaender - Viruses, 2021 - mdpi.com
SARS-CoV-2 has spread across the globe with an astonishing velocity and lethality that has put scientist and pharmaceutical companies worldwide on the spot to develop novel …
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the acute respiratory disease COVID-19, which has become a global concern due to its …
V Di Sarno, G Lauro, S Musella, T Ciaglia… - European Journal of …, 2021 - Elsevier
COVID-19 pandemic, starting from the latest 2019, and caused by SARS-CoV-2 pathogen, led to the hardest health-socio-economic disaster in the last century. Despite the …
FJ Redondo‐Calvo, JF Padín… - European Journal of …, 2022 - Wiley Online Library
Background SARS‐CoV‐2 virus requires host proteases to cleave its spike protein to bind to its ACE2 target through a two‐step furin‐mediated entry mechanism. Aprotinin is a broad …