Laboratory diagnosis of melioidosis: past, present and future

SKP Lau, S Sridhar, CC Ho, WN Chow… - Experimental …, 2015 - journals.sagepub.com
Melioidosis is an emerging, potentially fatal disease caused by Burkholderia pseudomallei,
which requires prolonged antibiotic treatment to prevent disease relapse. However …

[HTML][HTML] Melioidosis diagnostic workshop, 2013

AR Hoffmaster, D AuCoin, P Baccam… - Emerging infectious …, 2015 - ncbi.nlm.nih.gov
Melioidosis is a severe disease that can be difficult to diagnose because of its diverse
clinical manifestations and a lack of adequate diagnostic capabilities for suspected cases …

Development of rapid enzyme-linked immunosorbent assays for detection of antibodies to Burkholderia pseudomallei

V Suttisunhakul, V Wuthiekanun, PJ Brett… - Journal of clinical …, 2016 - Am Soc Microbiol
Burkholderia pseudomallei, the causative agent of melioidosis, is an environmental bacillus
found in northeast Thailand. The mortality rate of melioidosis is∼ 40%. An indirect …

How to determine the accuracy of an alternative diagnostic test when it is actually better than the reference tests: a re-evaluation of diagnostic tests for scrub typhus …

C Lim, DH Paris, SD Blacksell, A Laongnualpanich… - PloS one, 2015 - journals.plos.org
Background The indirect immunofluorescence assay (IFA) is considered a reference test for
scrub typhus. Recently, the Scrub Typhus Infection Criteria (STIC; a combination of culture …

Estimating the true accuracy of diagnostic tests for dengue infection using bayesian latent class models

W Pan-ngum, SD Blacksell, Y Lubell… - PloS one, 2013 - journals.plos.org
Background Accuracy of rapid diagnostic tests for dengue infection has been repeatedly
estimated by comparing those tests with reference assays. We hypothesized that those …

Melioidosis DS rapid test: A standardized serological dipstick assay with increased sensitivity and reliability due to multiplex detection

GE Wagner, E Föderl-Höbenreich, K Assig… - PLoS neglected …, 2020 - journals.plos.org
Background Melioidosis, caused by Burkholderia pseudomallei, is a severe infectious
disease with high mortality rates, but is under-recognized worldwide. In endemic areas …

[HTML][HTML] Evaluation of polysaccharide-based latex agglutination assays for the rapid detection of antibodies to Burkholderia pseudomallei

V Suttisunhakul, N Chantratita… - The American journal …, 2015 - ncbi.nlm.nih.gov
Melioidosis is a severe disease caused by the Gram-negative bacterium Burkholderia
pseudomallei. Diagnosis of melioidosis currently relies on the isolation of B. pseudomallei …

Optimal cutoff and accuracy of an IgM enzyme-linked immunosorbent assay for diagnosis of acute scrub typhus in northern Thailand: an alternative reference method …

SD Blacksell, C Lim… - Journal of clinical …, 2016 - Am Soc Microbiol
The enzyme-linked immunosorbent assay (ELISA) has been proposed as an alternative
serologic diagnostic test to the indirect immunofluorescence assay (IFA) for scrub typhus …

Evolving serodiagnostics by rationally designed peptide arrays: the Burkholderia paradigm in Cystic Fibrosis

C Peri, A Gori, P Gagni, L Sola, D Girelli, S Sottotetti… - Scientific Reports, 2016 - nature.com
Efficient diagnosis of emerging and novel bacterial infections is fundamental to guide
decisions on therapeutic treatments. Here, we engineered a novel rational strategy to design …

Production and evaluation of recombinant Burkholderia pseudomallei GroEL and OmpA proteins for serodiagnosis of melioidosis

K Kritsiriwuthinan, S Wajanarogana, K Choosang… - Acta tropica, 2018 - Elsevier
Melioidosis is a bacterial infectious disease caused by Burkholderia pseudomallei (B.
pseudomallei). The variable clinical manifestations of this disease make its diagnosis …