Polyamines as universal bioregulators across kingdoms and their role in cellular longevity and death

E Stolarska, E Paluch-Lubawa… - Critical Reviews in …, 2023 - Taylor & Francis
Polyamines (PAs) are important molecules that determine cell longevity or death. Studies
have shown that nutritional supplementation with spermidine can reduce age-related …

[HTML][HTML] The Synergistic Benefit of Combination Strategies Targeting Tumor Cell Polyamine Homeostasis

TA Liu, TM Stewart, RA Casero Jr - International Journal of Molecular …, 2024 - mdpi.com
Mammalian polyamines, including putrescine, spermidine, and spermine, are positively
charged amines that are essential for all living cells including neoplastic cells. An increasing …

eIF5A promotes+ 1 programmed ribosomal frameshifting in Euplotes octocarinatus

Y Xiao, J Li, R Wang, Y Fan, X Han, Y Fu… - International Journal of …, 2024 - Elsevier
Programmed ribosomal frameshifting (PRF) exists in all branches of life that regulate gene
expression at the translational level. The single-celled eukaryote Euplotes exhibit high …

Polyamines metabolism and their biological role in plant cells: what do we really know?

YS Kolesnikov, SV Kretynin, R Filepova… - Phytochemistry …, 2024 - Springer
In the present review, we concentrated on primary signaling and regulatory events in plant
cells that are rapidly evoked in response to extracellular polyamines in vivo and induce …

Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons

E Shojaeinia, TL Mastracci, R Soliman, O Devinsky… - Molecular Brain, 2024 - Springer
DHPS deficiency syndrome is an ultra-rare neurodevelopmental disorder (NDD) which
results from biallelic mutations in the gene encoding the enzyme deoxyhypusine synthase …

Plant metabolites and regulation under environmental stress

Á Szepesi - Plants, 2021 - mdpi.com
This Special Issue (SI) was planned to focus on abiotic stress-induced metabolic
adjustments and their regulations in plants. The purpose was achieved by collecting and …

Spermidine synthase is essential for vegetative growth, stress response, secondary metabolism and pathogenicity in Alternaria alternata

J Yuan, Y Liu, Y Yang, Y Li, M Zhang, X Wang… - Postharvest Biology and …, 2024 - Elsevier
Black spot, caused by the fungus Alternaria alternata, is one of the postharvest diseases that
cause significant economic losses. Polyamine metabolism in fungi plays key roles in cellular …

[HTML][HTML] Eukaryotic translation initiation factor OseIF5A4 negatively regulates rice immunity against blast and bacterial blight diseases

H Wang, Y Yan, Y Bi, D Li, F Song - The Crop Journal, 2025 - Elsevier
The RING-type E3 ligase OsBBI1 regulates rice resistance against Magnaporthe oryzae
through modifying cell wall defenses. In this study, we report the function of an OsBBI1 …

Effects of Perillaldehyde and Polyamines on Defense Mechanisms of Sweet Potatoes against Ceratocystis fimbriata

B Wang, S Wang, Q Geng, N Zhang… - Journal of Agricultural …, 2024 - ACS Publications
Sweet potato (Ipomoea batatas) serves as a significant food and economic crop worldwide.
However, its production and safety are jeopardized by black rot, a disease caused by …

[HTML][HTML] Proteome and metabolome of Annona crassiflora Mart. fruit and their interaction during development

CAR da Costa, SV do Nascimento… - Scientia …, 2025 - Elsevier
Abstract Marolo (Annona crassiflora Mart.) is an exotic fruit from the Brazilian Cerrado, rich in
various bioactive compounds. This unprecedented study analyzed through different …