Multifarious beneficial effect of nonessential amino acid, glycine: a review

MA Razak, PS Begum, B Viswanath… - … medicine and cellular …, 2017 - Wiley Online Library
Glycine is most important and simple, nonessential amino acid in humans, animals, and
many mammals. Generally, glycine is synthesized from choline, serine, hydroxyproline, and …

Intestinal amino acid transport and metabolic health

S Bröer - Annual review of nutrition, 2023 - annualreviews.org
Amino acids derived from protein digestion are important nutrients for the growth and
maintenance of organisms. Approximately half of the 20 proteinogenic amino acids can be …

[HTML][HTML] Glycine stimulates protein synthesis and inhibits oxidative stress in pig small intestinal epithelial cells

W Wang, Z Wu, G Lin, S Hu, B Wang, Z Dai, G Wu - The Journal of nutrition, 2014 - Elsevier
Glycine has recently been classified as a nutritionally essential amino acid for maximal
growth in young pigs. Currently, little is known about the metabolism or function of glycine in …

Beneficial effects of the amino acid glycine

I Pérez-Torres, A María Zuniga-Munoz… - Mini reviews in …, 2017 - ingentaconnect.com
Glycine is the smallest non-essential, neutral and metabolically inert amino acid, with a
carbon atom bound to two hydrogen atoms, and to an amino and a carboxyl group. This …

Defective intestinal amino acid absorption in Ace2 null mice

D Singer, SMR Camargo, T Ramadan… - American Journal …, 2012 - journals.physiology.org
Mutations in the main intestinal and kidney luminal neutral amino acid transporter B0AT1
(Slc6a19) lead to Hartnup disorder, a condition that is characterized by neutral …

[HTML][HTML] Short-chain fatty acids reprogram metabolic profiles with the induction of reactive oxygen species production in human colorectal adenocarcinoma cells

C Huang, W Deng, H Xu, C Zhou, F Zhang… - Computational and …, 2023 - Elsevier
Short-chain fatty acids (SCFAs) exhibit anticancer activity in cellular and animal models of
colon cancer. Acetate, propionate, and butyrate are the three major SCFAs produced from …

The neurotransmitters glycine and GABA stimulate glucagon‐like peptide‐1 release from the GLUTag cell line

A Gameiro, F Reimann, AM Habib… - The Journal of …, 2005 - Wiley Online Library
The incretin hormone, glucagon‐like peptide‐1 (GLP‐1) is released from intestinal L‐cells
following food ingestion. Its secretion is triggered by a range of nutrients, including fats …

Evaluating human intestinal cell lines for studying dietary protein absorption

PGM Jochems, J Garssen, AM Van Keulen… - Nutrients, 2018 - mdpi.com
With the global population rising, the need for sustainable and resource-efficiently produced
proteins with nutritional and health promoting qualities has become urgent. Proteins are …

Glycine transporter GLYT1 is essential for glycine‐mediated protection of human intestinal epithelial cells against oxidative damage

A Howard, I Tahir, S Javed, SM Waring… - The Journal of …, 2010 - Wiley Online Library
Glycine protects mammalian intestine against oxidative damage caused by ischaemia‐
reperfusion (IR) injury and prevents or reverses experimentally‐induced colitis. However the …

Protein digestion and absorption

YD Bhutia, V Ganapathy - Physiology of the gastrointestinal tract, 2018 - Elsevier
Dietary proteins undergo luminal digestion by gastric and pancreatic proteases and then
membrane digestion by peptidases associated with the brush border membrane of …