Preparation of large biological samples for high-resolution, hierarchical, synchrotron phase-contrast tomography with multimodal imaging compatibility

J Brunet, CL Walsh, WL Wagner, A Bellier, C Werlein… - Nature protocols, 2023 - nature.com
Imaging across different scales is essential for understanding healthy organ morphology
and pathophysiological changes. The macro-and microscale three-dimensional morphology …

[HTML][HTML] A practical guide for in situ mechanical testing of musculoskeletal tissues using synchrotron tomography

E Dall'Ara, AJ Bodey, H Isaksson, G Tozzi - journal of the mechanical …, 2022 - Elsevier
Musculoskeletal tissues are complex hierarchical materials where mechanical response is
linked to structural and material properties at different dimensional levels. Therefore, high …

[PDF][PDF] 3D virtual histology of human pancreatic tissue by multiscale phase-contrast X-ray tomography

J Frohn, D Pinkert-Leetsch… - Journal of …, 2020 - journals.iucr.org
A multiscale three-dimensional (3D) virtual histology approach is presented, based on two
configurations of propagation phase-contrast X-ray tomography, which have been …

Sintering and concomitant crystallization of bioactive glasses

C Blaeß, R Müller… - … Journal of Applied …, 2019 - Wiley Online Library
The sintering of bioactive glasses allows for the preparation of complex structures, such as
three‐dimensional porous scaffolds. Such 3D constructs are particularly interesting for …

[HTML][HTML] Contrast enhancement for visualizing neuronal cytoarchitecture by propagation-based x-ray phase-contrast tomography

M Töpperwien, A Markus, F Alves, T Salditt - NeuroImage, 2019 - Elsevier
Abstract Knowledge of the three-dimensional (3d) neuronal cytoarchitecture is an important
factor in order to understand the connection between tissue structure and function or to …

[HTML][HTML] Synchrotron tomography of intervertebral disc deformation quantified by digital volume correlation reveals microstructural influence on strain patterns

CM Disney, A Eckersley, JC McConnell, H Geng… - Acta biomaterialia, 2019 - Elsevier
The intervertebral disc (IVD) has a complex and multiscale extracellular matrix structure
which provides unique mechanical properties to withstand physiological loading. Low back …

A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta

WM Tun, G Poologasundarampillai… - Journal of The …, 2021 - royalsocietypublishing.org
Multi-scale structural assessment of biological soft tissue is challenging but essential to gain
insight into structure–function relationships of tissue/organ. Using the human placenta as an …

[HTML][HTML] From micro-to nano-and time-resolved x-ray computed tomography: Bio-based applications, synchrotron capabilities, and data-driven processing

PIC Claro, EPBS Borges, GR Schleder… - Applied Physics …, 2023 - pubs.aip.org
X-ray computed microtomography (μCT) is an innovative and nondestructive versatile
technique that has been used extensively to investigate bio-based systems in multiple …

Spatiotemporal and microstructural characterization of heterotopic ossification in healing rat Achilles tendons

M Pierantoni, M Hammerman, I Silva Barreto… - The FASEB …, 2023 - Wiley Online Library
Achilles tendon rupture is a common debilitating medical condition. The healing process is
slow and can be affected by heterotopic ossification (HO), which occurs when pathologic …

[HTML][HTML] Virtual histology of an entire mouse brain from formalin fixation to paraffin embedding. Part 2: Volumetric strain fields and local contrast changes

G Rodgers, C Tanner, G Schulz, A Migga, W Kuo… - Journal of Neuroscience …, 2022 - Elsevier
Background Fixation and embedding of post mortem brain tissue is a pre-requisite for both
gold-standard conventional histology and X-ray virtual histology. This process alters the …