Worldwide there have been over 760 million confirmed coronavirus disease 2019 (COVID-
19) cases, and over 13 billion COVID-19 vaccine doses have been administered as of April …

Despite their proven efficacy and huge contribution to the health of humankind, vaccines
continue to be a source of concern for some individuals around the world. Vaccinations …

Patients with severe infections and a pre-existing indication for antithrombotic therapy, ie
antiplatelet agents, anticoagulant drugs, or their combinations, require integrated clinical …

The world is presently in crisis facing an outbreak of a health‐threatening microorganism
known as COVID‐19, responsible for causing uncommon viral pneumonia in humans. The …

Here, we review the highlights of cardiovascular basic science published in 2021 and early
2022 on behalf of the European Society of Cardiology Council for Basic Cardiovascular …

Leukotrienes are important pro-inflammatory lipid mediators derived from the arachidonic
acid metabolism. In particular, cysteinyl leukotrienes, namely LTC4, LTD4, and LTE4 are …

Several vaccine-induced thrombotic thrombocytopenia syndrome (VITTS) cases have been
reported after the ChAdOx1 nCov-19 vaccination. The current study systematically reviewed …

Purpose: The aim of the study is to evaluate the effect of metformin in complication
improvement of hospitalized patients with COVID-19. Methods: This was a randomized …

The emergence of the COVID-19 pandemic has led to the rapid and worldwide development
and investigation of multiple vaccines. While most side effects of these vaccines are mild …

In this editorial, the section editors are looking back at 2022 by summarizing a few of the
many highlights in the EHJ Open content. All publications in EHJ Open are indexed in …