Obesity and insulin resistance are associated with the development of type 2 diabetes. It is
well accepted that beta cell dysfunction is required for hyperglycaemia to occur. The …

Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for
Pathogenesis* | Endocrine Reviews | Oxford Academic Skip to Main Content Advertisement …

The relative contributions of insulin resistance and beta-cell dysfunction to the
pathophysiology of Type 2 diabetes have been debated extensively. The concept that a …

Background Although the role of vitamin D in type 2 diabetes is well recognized, its relation
to glucose metabolism is not well studied. Objective We investigated the relation of 25 …

This statement examines the cardiovascular complications of diabetes mellitus and
considers opportunities for their prevention. These complications include coronary heart …

The TyG index was evaluated as a surrogate method for estimation of insulin resistance (IR).
TyG index correlated with adiposity, metabolic and atherosclerosis markers related to IR and …

The pathogenesis of type 2 diabetes involves abnormalities in insulin action, insulin
secretion, and endogenous glucose output (EGO). However, the sequence with which these …

A discussion of the pathogenesis of type 2 diabetes mellitus must start with a review of
mechanisms involved in the maintenance of normal glucose homeostasis in the basal or …

Task Forces, expert groups, or consensus panels. The chosen experts in these writing
panels are asked to provide disclosure statements of all relationships they may have, which …

OBJECTIVE: The oral glucose tolerance test (OGTT) has often been used to evaluate
apparent insulin release and insulin resistance in various clinical settings. However …