[HTML][HTML] Deep brain stimulation of thalamus for epilepsy

RS Fisher - Neurobiology of Disease, 2023 - Elsevier
Neuromodulation (neurostimulation) is a relatively new and rapidly growing treatment for
refractory epilepsy. Three varieties are approved in the US: vagus nerve stimulation (VNS) …

[HTML][HTML] Time to wake up: Studying neurovascular coupling and brain-wide circuit function in the un-anesthetized animal

YR Gao, Y Ma, Q Zhang, AT Winder, Z Liang, L Antinori… - Neuroimage, 2017 - Elsevier
Functional magnetic resonance imaging (fMRI) has allowed the noninvasive study of task-
based and resting-state brain dynamics in humans by inferring neural activity from blood …

Targeted suppression of mTORC2 reduces seizures across models of epilepsy

J Okoh, J Mays, A Bacq, JA Oses-Prieto… - Nature …, 2023 - nature.com
Epilepsy is a neurological disorder that poses a major threat to public health.
Hyperactivation of mTOR complex 1 (mTORC1) is believed to lead to abnormal network …

Solving brain circuit function and dysfunction with computational modeling and optogenetic fMRI

JH Lee, Q Liu, E Dadgar-Kiani - Science, 2022 - science.org
Can we construct a model of brain function that enables an understanding of whole-brain
circuit mechanisms underlying neurological disease and use it to predict the outcome of …

Frequency-selective control of cortical and subcortical networks by central thalamus

J Liu, HJ Lee, AJ Weitz, Z Fang, P Lin, MK Choy… - elife, 2015 - elifesciences.org
Central thalamus plays a critical role in forebrain arousal and organized behavior. However,
network-level mechanisms that link its activity to brain state remain enigmatic. Here, we …

[HTML][HTML] The hearing hippocampus

AJ Billig, M Lad, W Sedley, TD Griffiths - Progress in neurobiology, 2022 - Elsevier
The hippocampus has a well-established role in spatial and episodic memory but a broader
function has been proposed including aspects of perception and relational processing …

Memory and eating: A bidirectional relationship implicated in obesity

MB Parent, S Higgs, LG Cheke, SE Kanoski - … & Biobehavioral Reviews, 2022 - Elsevier
This paper reviews evidence demonstrating a bidirectional relationship between memory
and eating in humans and rodents. In humans, amnesia is associated with impaired …

Animal functional magnetic resonance imaging: trends and path toward standardization

F Mandino, DH Cerri, CM Garin, M Straathof… - Frontiers in …, 2020 - frontiersin.org
Animal whole-brain functional magnetic resonance imaging (fMRI) provides a non-invasive
window into brain activity. A collection of associated methods aims to replicate observations …

Functional connectivity of the brain across rodents and humans

N Xu, TJ LaGrow, N Anumba, A Lee, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the
spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is …

Low-frequency hippocampal–cortical activity drives brain-wide resting-state functional MRI connectivity

RW Chan, ATL Leong, LC Ho, PP Gao… - Proceedings of the …, 2017 - National Acad Sciences
The hippocampus, including the dorsal dentate gyrus (dDG), and cortex engage in
bidirectional communication. We propose that low-frequency activity in hippocampal …