[HTML][HTML] Autophagy as a gateway for the effects of methamphetamine: From neurotransmitter release and synaptic plasticity to psychiatric and neurodegenerative …

F Limanaqi, CL Busceti, R Celli, F Biagioni… - Progress in …, 2021 - Elsevier
As a major eukaryotic cell clearing machinery, autophagy grants cell proteostasis, which is
key for neurotransmitter release, synaptic plasticity, and neuronal survival. In line with this …

The HNRNPF/H RNA binding proteins and disease

T Brownmiller, NJ Caplen - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
The members of the HNRNPF/H family of heterogeneous nuclear RNA proteins—HNRNPF,
HNRNPH1, HNRNPH2, HNRNPH3, and GRSF1, are critical regulators of RNA maturation …

HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript

T Vo, T Brownmiller, K Hall, TL Jones… - Nucleic Acids …, 2022 - academic.oup.com
In the presence of physiological monovalent cations, thousands of RNA G-rich sequences
can form parallel G-quadruplexes (G4s) unless RNA-binding proteins inhibit, destabilize, or …

Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder

X Xue, W Zong, JR Glausier, SM Kim… - Translational …, 2022 - nature.com
Severe and persistent disruptions to sleep and circadian rhythms are common in people
with opioid use disorder (OUD). Preclinical evidence suggests altered molecular rhythms in …

Dopamine and methamphetamine differentially affect electron transport chain complexes and parkin in rat striatum: New insight into methamphetamine neurotoxicity

V Bazylianska, A Sharma, H Chauhan… - International journal of …, 2021 - mdpi.com
Methamphetamine (METH) is a highly abused psychostimulant that is neurotoxic to
dopaminergic (DAergic) nerve terminals in the striatum and increases the risk of developing …

[HTML][HTML] Alcohol-drinking under limited-access procedures during mature adulthood accelerates the onset of cognitive impairment in mice

CL Jimenez Chavez, E Van Doren… - Frontiers in Behavioral …, 2022 - frontiersin.org
A history of heavy drinking increases vulnerability to, and the severity of, Alzheimer's
Disease (AD) and related dementias, with Alcohol Use Disorder (AUD) identified as the …

Inflammasome inhibition prevents motor deficit and cerebellar degeneration induced by chronic methamphetamine administration

J Ding, L Shen, Y Ye, S Hu, Z Ren, T Liu… - Frontiers in Molecular …, 2022 - frontiersin.org
Methamphetamine (METH), a psychostimulant, has the potential to cause
neurodegeneration by targeting the cerebrum and cerebellum. It has been suggested that …

Trajectories of craving in the course of pharmacotherapy trials for methamphetamine use disorder

R Mojtabai, R Susukida, M Farokhnia, TQ Nguyen… - …, 2024 - Wiley Online Library
Aims The aim of this study was to measure trajectories of craving for methamphetamine
during the course of pharmacotherapy trials for methamphetamine use disorder. Design …

Characterization of the microRNA transcriptomes and proteomics of cochlear tissue-derived small extracellular vesicles from mice of different ages after birth

P Jiang, X Ma, S Han, L Ma, J Ai, L Wu, Y Zhang… - Cellular and Molecular …, 2022 - Springer
The cochlea is an important sensory organ for both balance and sound perception, and the
formation of the cochlea is a complex developmental process. The development of the …

Sex‐dependent effects of an Hnrnph1 mutation on fentanyl addiction‐relevant behaviors but not antinociception in mice

CD Bryant, AF Healy, QT Ruan… - Genes, brain and …, 2021 - Wiley Online Library
Abstract Opioid Use Disorder (OUD) and opioid‐related deaths remain a major public health
concern in the United States. Both environmental and genetic factors influence risk for OUD …