It has become evident that mechanical forces play a key role in cancer metastasis, a
complex series of steps that is responsible for the majority of cancer-related deaths. One …

Fluid mechanics is involved in the growth, progression, metastasis, and therapy of cancer.
Blood vessels transport oxygen and nutrients to cancerous tissues, provide a route for …

Leukocyte recruitment to sites of inflammation is initiated by their tethering and rolling on the
activated endothelium under flow. Even though the fast kinetics and high tensile strength of …

Solid tumor dissemination from the primary site to the sites of metastasis involves tumor cell
transport through the blood or lymph circulation systems. Once the tumor cells enter the …

We present a computational methodology for modeling cellular-scale blood flow in arbitrary
and highly complex geometry. Our approach is based on immersed-boundary methods …

Progress in cell purification technology is critical to increase the availability of viable cells for
therapeutic, diagnostic, and research applications. A variety of techniques are now available …

A particle method for the computer simulation of blood flow was proposed to analyze the
motion of a deformable red blood cell (RBC) in flowing blood plasma. The RBC and plasma …

An ultrasound‐based molecular imaging technique capable of detecting endothelial cell
markers of inflammation may allow early, non‐invasive assessment of vascular disease …

Historically, predicting macroscopic blood flow characteristics such as viscosity has been an
empirical process due to the difficulty in rigorously including the particulate nature of blood …

A cell-scaled microbead system was used to analyze the force-dependent kinetics of P-
selectin adhesive bonds independent of micromechanical properties of the neutrophil's …