Over the years, the mitochondrial fatty acid β-oxidation (FAO) pathway has been
characterised at the biochemical level as well as the molecular biological level. FAO plays a …

Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …

Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …

Identifying the genomic changes that underlie phenotypic adaptations is a key challenge in
evolutionary biology and genomics. Loss of protein-coding genes is one type of genomic …

1704 Circulation Research May 27, 2016 of epigenetic mechanisms contributing to
macrovascular disease in diabetes. The authors highlight the recent identification of …

The uptake and metabolism of long chain fatty acids (LCFA) are critical to many
physiological and cellular processes. Aberrant accumulation or depletion of LCFA underlie …

Long-chain fatty acyl-coenzyme As (CoAs) are critical regulatory molecules and metabolic
intermediates. The initial step in their synthesis is the activation of fatty acids by one of 13 …

Pork is one of the main meats consumed by people, and its nutritional value is closely
related to human health. The lipid deposition and composition of pork not only affect the …

J. Neurochem.(2011) 117, 735–746. Abstract The blood‐brain barrier (BBB), formed by the
brain capillary endothelial cells, provides a protective barrier between the systemic blood …

Uptake of long-chain fatty acids plays pivotal roles in metabolic homeostasis and human
physiology. Uptake rates must be controlled in an organ-specific fashion to balance storage …