[HTML][HTML] Overview of methods for enhancing bone regeneration in distraction osteogenesis: potential roles of biometals

Y Li, Q Pan, J Xu, X He, HA Li, DA Oldridge, G Li… - Journal of orthopaedic …, 2021 - Elsevier
Background Distraction osteogenesis (DO) is a functional tissue engineering approach that
applies gradual mechanical traction on the bone tissues after osteotomy to stimulate bone …

Effects of low-intensity pulsed ultrasound therapy on fracture healing: a systematic review and meta-analysis

SB Tajali, P Houghton, JC MacDermid… - American journal of …, 2012 - journals.lww.com
Objective This systematic review and meta-analysis was performed to identify the clinical
trials relevant to the effects of low-intensity pulsed ultrasound (LIPUS) on bone regeneration …

Micro-computed tomography assessment of fracture healing: relationships among callus structure, composition, and mechanical function

EF Morgan, ZD Mason, KB Chien, AJ Pfeiffer… - Bone, 2009 - Elsevier
Non-invasive characterization of fracture callus structure and composition may facilitate
development of surrogate measures of the regain of mechanical function. As such …

The response of bone to mechanical loading and disuse: fundamental principles and influences on osteoblast/osteocyte homeostasis

TM Skerry - Archives of biochemistry and biophysics, 2008 - Elsevier
Bone's response to increased or reduced loading/disuse is a feature of many clinical
circumstances, and our daily life, as habitual activities change. However, there are several …

Ultrasound for fracture healing: current evidence

Y Watanabe, T Matsushita, M Bhandari… - … of orthopaedic trauma, 2010 - journals.lww.com
Low-intensity pulsed ultrasound (LIPUS) is a relatively new technique for the acceleration of
fracture healing in fresh fractures and nonunions. It has a frequency of 1.5 MHz, a signal …

Low‐magnitude high‐frequency vibration accelerates callus formation, mineralization, and fracture healing in rats

KS Leung, HF Shi, WH Cheung, L Qin… - Journal of …, 2009 - Wiley Online Library
Fracture healing is a biological regenerative process that follows a well‐orchestrated
sequence. Most healing is uneventful and enhancement of normal fracture healing is not …

Low-intensity pulsed ultrasound accelerated bone-tendon junction healing through regulation of vascular endothelial growth factor expression and cartilage formation

H Lu, L Qin, W Cheung, K Lee, W Wong… - Ultrasound in medicine & …, 2008 - Elsevier
The purpose of this study was to use our established partial patellectomy rabbit model to
study the effects of low-intensity pulsed ultrasound (LIPUS) on patella-patellar tendon (PPT) …

Osthole enhances osteogenesis in osteoblasts by elevating transcription factor osterix via cAMP/CREB signaling in vitro and in vivo

ZR Zhang, WN Leung, G Li, SK Kong, X Lu, YM Wong… - Nutrients, 2017 - mdpi.com
Anabolic anti-osteoporotic agents are desirable for treatment and prevention of osteoporosis
and fragility fractures. Osthole is a coumarin derivative extracted from the medicinal herbs …

Low-intensity pulsed ultrasound on tendon healing: a study of the effect of treatment duration and treatment initiation

SC Fu, WT Shum, LK Hung… - … American journal of …, 2008 - journals.sagepub.com
Background Low-intensity pulsed ultrasound has been reported to be effective in promoting
tendon healing. However, its optimal time and duration has not yet been determined …

[PDF][PDF] Biomaterial osseointegration enhancement with biophysical stimulation

R Dimitriou, GC Babis - J Musculoskelet Neuronal Interact, 2007 - ismni.org
Despite the ongoing improvement in implant characteristics, bone intrinsic potential for
regeneration may be stimulated with adjuvant therapies to standard surgical procedures, as …