Orofacial clefts (OFCs) rank as the second most common congenital birth defect in the
United States after Down syndrome and are the most common head and neck congenital …

Cleft lip and/or cleft palate (CL/P) collectively are well known as being amongst the most
common birth defects but we still have difficulty explaining why the majority of cases occur …

Background The genetic cause of intellectual disability in most patients is unclear because
of the absence of morphological clues, information about the position of such genes, and …

Balanced chromosomal abnormalities (BCAs) represent a relatively untapped reservoir of
single-gene disruptions in neurodevelopmental disorders (NDDs). We sequenced BCAs in …

Induced osteogenesis includes a program of microRNAs (miRs) to repress the translation of
genes that act as inhibitors of bone formation. How expression of bone-related miRs is …

Nonsyndromic orofacial clefts (OFCs) are a heterogeneous group of common craniofacial
birth defects with complex etiologies that include genetic and environmental risk factors …

Aims Diagnosing osteosarcoma can be challenging, as osteoid deposition is often limited in
extent, and hyalinized stroma may closely mimic osteoid. SATB 2 is a nuclear protein that …

Non syndromic orofacial clefts specifically non-syndromic cleft lip/palate are one of the most
common craniofacial malformation among birth defects in human having multifactorial …

Epigenetic control of gene expression programs is essential for normal organismal
development and cellular function. Abrogation of epigenetic regulation is seen in many …

Clefts of the palate are common birth defects requiring extensive treatment. They appear to
be caused by multiple genetic and environmental factors during palatogenesis. This may …