In July 2022, these guidelines were reviewed by an expert work group convened by ASH.
Review included limited searches for new evidence and discussion of the search results …

Blood transfusion is one of the most common procedures in patients in hospital so it is
imperative that clinicians are knowledgeable about appropriate blood product …

While red blood cell (RBC) transfusion is the most common medical intervention in
hospitalized patients, as with any therapeutic, it is not without risk. Allogeneic RBC exposure …

Transfusions can be a life-saving treatment of patients with sickle-cell disease (SCD).
However, availability of matched units can be limiting because of distinctive blood group …

A hemolytic transfusion reaction (HTR) is the accelerated clearance or destruction of red
blood cells associated with a transfusion event. Causes of HTRs and differential diagnoses …

Delayed hemolytic transfusion reaction (DHTR) is a life‐threatening complication of
transfusion in sickle cell disease (SCD). The frequency of DHTR is underestimated because …

Delayed hemolytic transfusion reaction (DHTR) is one of the most feared complications of
sickle‐cell disease (SCD). We retrospectively analyzed the clinical and biological features …

1Whittington Health, 2Barts Health NHS Trust & NHS Blood and Transplant, London,
3Oxford University Hospitals NHS Foundation Trust, Oxford, 4University College London …

Patients with sickle cell disease (SCD) often receive red blood cell (RBC) transfusion
support for the prevention and management of many acute and chronic disease …

Transfusion therapy is effective in the prevention and treatment of many complications of
sickle cell disease (SCD). However, its benefits must be balanced against its risks, including …