Zanthoxylum Species: A Review of Traditional Uses, Phytochemistry and Pharmacology in Relation to Cancer, Infectious Diseases and Sickle Cell Anemia

IU Okagu, JC Ndefo, EC Aham… - Frontiers in …, 2021 - frontiersin.org
The health benefits and toxicity of plant products are largely dependent on their secondary
metabolite contents. These compounds are biosynthesized by plants as protection …

Activity of the genus Zanthoxylum against diseases caused by protozoa: A systematic review

J Correa-Barbosa, DF Sodré… - Frontiers in …, 2023 - frontiersin.org
Neglected diseases (NDs) are treated with a less varied range of drugs, with high cost and
toxicity, which makes the search for therapeutic alternatives important. In this context, plants …

Does mangrove vegetation structure reflect human utilization of ecosystem goods and services?

F Asante, J Huge, NK Asare, F Dahdouh-Guebas - Iscience, 2023 - cell.com
Many coastal communities in developing countries depend on mangrove ecosystem
services (ES). A combination of anthropogenic and environmental stresses threatens …

[HTML][HTML] Microalgae extracts: Potential anti-Trypanosoma cruzi agents?

R Veas, M Rojas-Pirela, C Castillo, C Olea-Azar… - Biomedicine & …, 2020 - Elsevier
Introduction Chagas disease, caused by the protozoan parasiteTrypanosoma cruzi, has no
effective treatment available. On the other hand, microalgae are aquatic organisms that …

Zanthoxylum zanthoxyloides Alkaloidal Extract Improves CCl4‐Induced Hepatocellular Carcinoma‐Like Phenotypes in Rats

DO Acheampong, IK Baffour… - Evidence‐Based …, 2021 - Wiley Online Library
Background. Despite the enrollment of new small molecules such as Sorafenib for the
treatment of hepatocellular carcinoma (HCC), HCC still remains a significant contributor to …

Isolation and Antitrypanosomal Characterization of Furoquinoline and Oxylipin from Zanthoxylum zanthoxyloides

AK Dofuor, F Ayertey, P Bolah, GI Djameh, K Kyeremeh… - Biomolecules, 2020 - mdpi.com
In the absence of vaccines, there is a need for alternative sources of effective chemotherapy
for African trypanosomiasis (AT). The increasing rate of resistance and toxicity of …

[HTML][HTML] In vitro effects and mechanisms of action of Bidens pilosa in Trypanosoma brucei

AK Dofuor, GI Djameh, M Amoa-Bosompem… - Journal of traditional and …, 2022 - Elsevier
Background and aim African trypanosomiasis poses serious health and economic concerns
to humans and livestock in several sub-Saharan African countries. The aim of the present …

Antileishmanial, antitrypanosomal and anti-coronavirus activities of benzophenanthridine alkaloids and other specialized metabolites isolated from the root bark of …

A Ba, V Roumy, M Al Ibrahim, K Hughes, T Hennebelle… - Fitoterapia, 2024 - Elsevier
Strong antileishmanial and antitrypanosomal activities were highlighted for the crude
methanolic extract (IC 50= 0.61 and 2.15 μg/mL, respectively) of Zanthoxylum …

Therapeutic evaluation of anti-trypanosoma activity of ethanol extracts of Jatropha curcas roots in comparison with diminazene aceturate in Trypanosoma brucei …

OH Okwor, VN Ogugua, IU Okagu - Comparative Clinical Pathology, 2020 - Springer
Jatropha curcas is used as an old herbal therapy in the treatment of several vector-borne
diseases in several parts of Africa. Considering the burden of trypanosoma infection and the …

In vitro inhibitory effect of leaf and seed extracts of Moringa oleifera on growth of Fusarium oxysporum associated with leaf spots of Zanthoxylum zanthoxyloides

OFA Ibiam, FW Nmom, EC Nwaru, IN Bassey… - …, 2023 - journals.pu.edu.pk
Fusarium oxysporum was found associated with the leaf spot disease of Zanthxylum
zanthoxyloides. The goal of this study was to employ Moringa oleifera aqueous leaf and …