Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

The sympathetic nervous system (SNS) is known to play a pivotal role in short-and long-term
regulation of different functions of the cardiovascular system. In the past decades increasing …

Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …

There is growing evidence to suggest that many disease states are accompanied by chronic
elevations in sympathetic nerve activity. The present review will specifically focus on central …

The pineal hormone, melatonin (N-acetyl-5-methoxytryptamine), shows potent receptor-
dependent and-independent actions, which participate in blood pressure regulation. The …

This review describes and summarizes the role of neuronal nitric oxide synthase (nNOS) on
the central nervous system, particularly on brain regions such as the ventrolateral medulla …

The production of the pineal hormone melatonin is synchronized with day-night cycle via
multisynaptic pathway including suprachiasmatic nucleus linking several physiological …

The identification of novel endogenous and exogenous molecules acting in the complex
mechanism of regulating the vascular tonus has always been of great interest. The discovery …

Background—HMG-CoA reductase inhibitors (statins) have been shown to beneficially affect
outcomes in chronic heart failure (CHF). We hypothesized that statins exert effects on …