A BAG's life: Every connection matters in cancer

E Mariotto, G Viola, C Zanon, S Aveic - Pharmacology & Therapeutics, 2020 - Elsevier
The members of the BCL-2 associated athanogene (BAG) family participate in the regulation
of a variety of interrelated physiological processes, such as autophagy, apoptosis, and …

YAP tyrosine phosphorylation and nuclear localization in cholangiocarcinoma cells are regulated by LCK and independent of LATS activity

T Sugihara, NW Werneburg, MC Hernandez… - Molecular Cancer …, 2018 - AACR
Abstract The Hippo pathway effector, Yes-associated protein (YAP), is a transcriptional
coactivator implicated in cholangiocarcinoma (CCA) pathogenesis. YAP is known to be …

[HTML][HTML] Differentially expressed autophagy-related genes are potential prognostic and diagnostic biomarkers in clear-cell renal cell carcinoma

B Wan, B Liu, G Yu, Y Huang, C Lv - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
We examined the role of differentially expressed autophagy-related genes (DEARGs) in
clear cell Renal Cell Carcinoma (ccRCC) using high-throughput RNA-seq data from The …

Comparative analysis of BAG1 and BAG2: Insights into their structures, functions and implications in disease pathogenesis

M Hou, M Yue, X Han, T Sun, Y Zhu, Z Li, J Han… - International …, 2024 - Elsevier
As BAG family members, Bcl-2 associated athanogene family protein 1 (BAG1) and 2
(BAG2) are implicated in multiple cellular processes, including apoptosis, autophagy …

OSkirc: a web tool for identifying prognostic biomarkers in kidney renal clear cell carcinoma

L Xie, Q Wang, Y Dang, L Ge, X Sun, N Li, Y Han… - Future …, 2019 - Taylor & Francis
Aim: To develop a free and quick analysis online tool that allows users to easily investigate
the prognostic potencies of interesting genes in kidney renal clear cell carcinoma (KIRC) …

Development and clinical validation of a seven-gene prognostic signature based on multiple machine learning algorithms in kidney cancer

M Tian, T Wang, P Wang - Cell Transplantation, 2021 - journals.sagepub.com
About a third of patients with kidney cancer experience recurrence or cancer-related
progression. Clinically, kidney cancer prognoses may be quite different, even in patients …

Prognostic Value of Plasma hPG80 (Circulating Progastrin) in Metastatic Renal Cell Carcinoma

M Kohli, W Tan, B Vire, P Liaud, M Blairvacq, F Berthier… - Cancers, 2021 - mdpi.com
Simple Summary Metastatic renal cell carcinoma (mRCC) accounts for one-third of all newly
diagnosed renal cell cancers. A better understanding of the biology and molecular basis of …

Identification of methylation‐driven genes related to prognosis in clear‐cell renal cell carcinoma

J Wang, Q Zhang, Q Zhu, C Liu, X Nan… - Journal of Cellular …, 2020 - Wiley Online Library
With the participation of the existing treatment methods, the prognosis of advanced clear‐
cell renal cell carcinoma (ccRCC) is poor. More evidence indicates the presence of …

[HTML][HTML] Maternal nicotine exposure promotes hippocampal CeRNA-mediated excitotoxicity and social barriers in adolescent offspring mice

Y Zhao, B Li, H Cao, F Wang, M Mu, H Jin, J Liu… - Ecotoxicology and …, 2024 - Elsevier
Nicotine, an addictive component of cigarettes, causes cognitive defects, particularly when
exposure occurs early in life. However, the exact mechanism through which nicotine causes …

[HTML][HTML] ALDH3A1 driving tumor metastasis is mediated by p53/BAG1 in lung adenocarcinoma

F Fan, R Yin, L Wang, S Zhao, D Lv, K Yang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Lung adenocarcinoma (LUAD) is a lethal malignancy with metastasis, a major tumor feature
that predominantly correlated with progression, but the molecules that mediated tumor …