Factor XI deficiency: phenotypic age-related considerations and clinical approach towards bleeding risk assessment
AA Barg, T Livnat, G Kenet - Blood, 2024 - Elsevier
Factor XI (FXI) deficiency is a rare bleeding disorder that presents complex challenges in
patient assessment and bleeding risk management. Despite generally causing mild to …
patient assessment and bleeding risk management. Despite generally causing mild to …
Tissue factor pathway inhibitor is a potential modifier of bleeding risk in factor XI deficiency
SE Reitsma, LA Holle, EG Bouck, DM Monroe… - Journal of Thrombosis …, 2023 - Elsevier
Abstract Background Factor (F) XI deficiency is associated with increased bleeding risk in
some individuals. Neither FXI levels nor clinical clotting assays predict the bleeding risk …
some individuals. Neither FXI levels nor clinical clotting assays predict the bleeding risk …
Beyond uterine atony: characterizing postpartum hemorrhage coagulopathy
JR Coleman, S Fabbri, M Anderson, EE Moore… - American Journal of …, 2023 - Elsevier
BACKGROUND Postpartum hemorrhage is a leading cause of morbidity and mortality
worldwide, yet the associated early coagulopathy is not well defined. OBJECTIVE We …
worldwide, yet the associated early coagulopathy is not well defined. OBJECTIVE We …
Molecular and clinical characterization of two unrelated families with factor V deficiency, including a novel nonsense variant (p. Gln1532*)
K Zhang, L Ye, Y Jin, Y Chen, S Jiang, H Xie… - Blood Cells, Molecules …, 2024 - Elsevier
Abstract Background Factor V (FV) is an essential cofactor in the coagulation cascade. The
characterization of novel mutations is advantageous for the clinical management of FV …
characterization of novel mutations is advantageous for the clinical management of FV …