Inherited cardiomyopathies are a major cause of mortality and morbidity worldwide and can
be caused by mutations in a wide range of proteins located in different cellular …

Cardiomyopathy (CMP) is a rare disease in the pediatric population, with a high risk of
morbidity and mortality. The genetic etiology of CMPs in children is extremely heterogenous …

Genetic variants in gene-encoding proteins involved in cell–cell connecting structures, such
as desmosomes and gap junctions, may cause a skin and/or cardiac phenotype, of which …

Sudden cardiac death (SCD) accounts for approximately 15%–20% of all deaths worldwide,
the causes of which are mainly structural heart diseases. However, SCD also occurs in …

Heart failure (HF) is a clinical condition distinguished by structural and functional defects in
the myocardium, which genetic and environmental factors can induce. HF is caused by …

Background Hailey-Hailey disease (HHD) is a rare autosomal dominant skin disease
caused by mutations in the ATP2C1 gene, which encodes the secretory Ca2+/Mn2+-ATPase …

Introduction Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare inherited
disorder usually affecting the right ventricle (RV), characterized by fibro‐fatty tissue …

Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease associated with
ventricular arrhythmias and a high risk of sudden cardiac death (SCD). Although the disease …

Naxos disease (McKusick# 601214) is an inherited disorder associating arrhythmogenic
right ventricular cardiomyopathy (ARVC) with palmoplantar keratoderma (PPK), as well as …

Introduction: Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a rare inherited
disorder usually affecting the right ventricle (RV), characterized by fibro-fatty tissue …