Direct C–H bond arylation of (hetero) arenes is a very convenient approach for the synthesis
of a wide variety of molecular targets, including compounds of pharmaceutical interest and π …

Improved laboratory protocols for convenient and rapid transformations are highly desired in
modern synthetic chemistry. Microwave irradiated reactions have received considerable …

Conditions for the palladium-catalyzed direct arylation of a wide range of heterocycles with
aryl bromides are reported. Those conditions employ a stoichiometric ratio of both coupling …

(Hetero) aryl groups directly connected by single Csp2–Csp2 bonds to heteroaryl moieties
are present as core structures in many biologically active compounds, 1 naturally-occurring …

Direct and rapid heating by microwave irradiation in combination with sealed vessel
processing in many cases enables reactions to be carried out in a fraction of the time …

Combretastatin A-4 (CA-4) in phosphate and serine pro-drug forms is under phase II clinical
trials. With our interest of discovering CA-4 inspired new chemical entities, a novel series of …

Direct arylation is a useful method for the preparation of (hetero) aryl–aryl systems by C–H
bond cleavage. This procedure has several advantages such as the reduction of cost, time …

An efficient one-pot procedure for the synthesis of ionic liquids based on nitrogen-containing
heterocycles, imidazolium or pyridinium under 'green chemistry'conditions has been …

An expeditious catalyst-free heteroannulation reaction for imidazo [1, 2-a]
pyridines/pyrimidines/pyrazines was developed in green solvent under microwave …

The development of new strategies for the synthesis of fused heterocycles has remained a
highly attractive but challenging proposition. An overview of the application of microwave …