Oral candidiasis, commonly referred to as “thrush,” is an opportunistic fungal infection that
commonly affects the oral mucosa. The main causative agent, Candida albicans, is a highly …

The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Intestinal microbiota dysbiosis can initiate overgrowth of commensal Candida species–a
major predisposing factor for disseminated candidiasis. Commensal bacteria such as …

Candida albicans is the most common human fungal pathogen causing diseases ranging
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …

The polymorphic fungus Candida albicans is a member of the normal human microbiome. In
most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain …

The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial
pathogens which disrupt epithelial barrier function, damage cells and activate or modulate …

Highlights•Candidalysin is the first peptide toxin identified in any human fungal pathogen.•
Candidalysin is critical for Candida albicans mucosal and systemic infections.•Candidalysin …

The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …

An imbalance of the normal microbial flora, breakage of epithelial barriers or dysfunction of
the immune system favour the transition of the human pathogenic yeast Candida albicans …