Equine metabolic syndrome (EMS) is important because of its association with laminitis.
Obesity and insulin resistance are two important components of EMS, and the underlying …

Endotoxin (lipopolysaccharides; LPS) plays a pivotal role in many pathophysiological states
and diseases. Although the major pathways involved in LPS signal transduction are …

Objective—To determine the metabolic phenotype of a group of laminitis-prone ponies when
at pasture in summer, compared with when at pasture in winter. Animals—40 ponies of …

* The editors and authors acknowledge and appreciate the contributions of Samuel L.
Jones, Katharina I. Lohmann, Michelle Henry Barton, Laura Javsicas, Anthony T. Blikslager …

Objective—To identify risk factors for development of acute laminitis in horses during
hospitalization for illness or injury. Design—Retrospective case-control study. Animals—73 …

The link between the fermentation of carbohydrate in the equine large intestine and the
development of acute laminitis is poorly understood. Absorption of endotoxin …

Reasons for performing study: Endotoxaemia is frequently presumed on the basis of clinical
signs in horses with colic. Objective: Measurements of plasma endotoxin (LPS) are rarely …

The extracellular matrix (ECM) of connective tissue is constantly being remodelled to allow
for growth and regeneration. Normal tissue maintenance requires the ECM components to …

Epidemiologic studies indicate that most laminitis cases occur in horses and ponies kept at
pasture, hence the term pasture-associated laminitis. Clinical cases of laminitis most often …

Laminitis occurs throughout the world in horses and ponies and has major welfare
implications. It is obviously important to be able to recognize and treat the condition in its …