Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Management of moderate to severe traumatic brain injury: an update for the intensivist

G Meyfroidt, P Bouzat, MP Casaer, R Chesnut… - Intensive care …, 2022 - Springer
Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

[HTML][HTML] Guidelines for the management of severe traumatic brain injury: 2020 update of the decompressive craniectomy recommendations

GWJ Hawryluk, AM Rubiano, AM Totten, C O'Reilly… - …, 2020 - journals.lww.com
When the fourth edition of the Brain Trauma Foundation's Guidelines for the Management of
Severe Traumatic Brain Injury were finalized in late 2016, it was known that the results of the …

Intracranial pressure: current perspectives on physiology and monitoring

GWJ Hawryluk, G Citerio, P Hutchinson, A Kolias… - Intensive care …, 2022 - Springer
Intracranial pressure (ICP) monitoring is now viewed as integral to the clinical care of many
life-threatening brain insults, such as severe traumatic brain injury, subarachnoid …

Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus

C Robba, D Poole, M McNett, K Asehnoune… - Intensive care …, 2020 - Springer
Purpose To provide clinical practice recommendations and generate a research agenda on
mechanical ventilation and respiratory support in patients with acute brain injury (ABI) …

Intracranial pressure monitoring in patients with acute brain injury in the intensive care unit (SYNAPSE-ICU): an international, prospective observational cohort study

C Robba, F Graziano, P Rebora, F Elli… - The Lancet …, 2021 - thelancet.com
Background The indications for intracranial pressure (ICP) monitoring in patients with acute
brain injury and the effects of ICP on patients' outcomes are uncertain. The aims of this study …

Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial

K Baksaas-Aasen, LS Gall, J Stensballe… - Intensive care …, 2021 - Springer
Purpose Contemporary trauma resuscitation prioritizes control of bleeding and uses major
haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine …

Targeting autoregulation-guided cerebral perfusion pressure after traumatic brain injury (COGiTATE): a feasibility randomized controlled clinical trial

J Tas, E Beqiri, RC van Kaam, M Czosnyka… - Journal of …, 2021 - liebertpub.com
Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …

A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury …

R Chesnut, S Aguilera, A Buki, E Bulger, G Citerio… - Intensive care …, 2020 - Springer
Background Current guidelines for the treatment of adult severe traumatic brain injury (sTBI)
consist of high-quality evidence reports, but they are no longer accompanied by …

Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study

CAI Åkerlund, A Holst, N Stocchetti, EW Steyerberg… - Critical care, 2022 - Springer
Abstract Background While the Glasgow coma scale (GCS) is one of the strongest outcome
predictors, the current classification of traumatic brain injury (TBI) as 'mild','moderate'or …